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Project - USMLE Step 3 > Psychiatry: Pharm > Flashcards

Psychiatry: Pharm Flashcards

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USMLE® Step 1 flashcards
1
Q

Sx of neurleptic malignant syndrome (NMS)

A

Fever, Encephalopathy, Vitals unstable, Elevated enzymes, Rigidity of muscle

This is remembered by the acronym FEVER.

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2
Q

MAOIs

A

Tranylcypromine, Phenelzine, Isocarboxazid, Selegiline (selective MAO-B inhibitor)

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3
Q

SE of mirtazapine

A

sedation, inc appetite, weight gain, dry mouth

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4
Q

Halazepam (Paxipam): class and use

A

Benzodiazipines fo anxiety

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5
Q

Tx for tourette’s syndrome

A

antipsychotics (haloperidol, risperidone)

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6
Q

Carbidopa-levodopa (Sinemet): use

A

Parkinson disease

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7
Q

Venlafaxine (Effexor): class

A

Dual-acting SNRI

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8
Q

Aripiperazole (Abilify): class

A

New antipsychotic

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9
Q

Lithium: class

A

Mood stabilizer

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10
Q

SSRIs

A

Fluoxetine, Paroxetine, sertraline, Fluvoxamine, citalopram

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11
Q

Mesoridazine (serentil): class

A

Older Antpsychotic: Low potency

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12
Q

SE of chlorpromazine

A

corneal deposits, sedation, anticholinergic effects

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13
Q

Amitriptyline (Elavil): class

A

Tricyclic antidepressants TCA

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14
Q

Clonazepam (klonopin): class and use

A

Benzodiazipines fo anxiety

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15
Q

Donepezil (aricept): use

A

acetylcholinesterase inhibitor for Alzheimer’s disease

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16
Q

SE of haloperidol

A

neuroleptic malignant syndrome, tardive dyskinesia

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17
Q

SNRIs

A

venlafaxine, duloxetine

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18
Q

Trimipramine (Surmontil): class

A

Tricyclic antidepressants TCA

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19
Q

atypical antipsychotics

A

Olanzapine, clozapine, quietiapine, risperidone, aripiprazole, ziprasidone

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20
Q

action of bupropion

A

Atypical antidepressant that primarily acts as a mild dopamine reuptake inhibitor and a much weaker norepinephrine reuptake inhibitor as well as a nicotinic acetylcholine receptor antagonist. It does not cause weight gain or sexual dysfunction but does reduce the seizure threshold

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21
Q

Tx for schizophrenia

A

antipsychotics

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22
Q

Tx for alcohol withdrawl

A

benzodiazepine

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23
Q

Chlordiazepoxide (Librium): class and use

A

Benzodiazipines fo anxiety

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24
Q

SE of lithium

A

tremor, sedation, edema, heart block, hypothyroidism, polyuria(ADH antagonist), and teratogenesis

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25
Q

Paroxetine (PAxil): class

A

SSRI

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26
Q

Tx for anxiety

A

SSRI, SNRI, buspirone

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27
Q

Tx for ADHD

A

methylphenidate, amphetamines

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28
Q

Tx for Bipolar disorder

A

lithium, valproic acid, carbamazepines

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29
Q

nortiptyline (Pamelor): class

A

Tricyclic antidepressants TCA

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30
Q

Buspirone (BuSpar): class and use

A

Misc drug, anxiety

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31
Q

drugs used to Tx fibromyalgia

A

TCAs

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32
Q

Sx of serotonin syndrome

A

Hyperthermia, confusion, myoclonus, CV collapse, flushing, diarrhea, seizures

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33
Q

Sx of tardive dyskinesia

A

stereotypic oral-facial movements as a result of long term antipsychotic use

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34
Q

SE of thioridazine

A

retinal deposits, QT prolongation

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35
Q

SE of TCAs

A

Convulsion, Coma, Cardiotoxicity

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36
Q

endocrine SE of antipsychotics

A

antagonism of dopamine receptor–> hyperprolactinemia–> galactorrhea

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37
Q

Valproic Aid: class

A

Mood stabilizer

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38
Q

Clorazepete (Tranxene): class and use

A

Benzodiazipines for anxiety

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39
Q

Bupropion (Wellbutrin): class

A

Dual-acting DNRI

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40
Q

Tx for NMS

A

Dantrolene or D2 agonist (bromocriptine)

41
Q

Duloxetine (Cymbalta): class

A

Dual-acting SNRI

42
Q

Ziprasidone (Geodon): class

A

New antipsychotic

43
Q

Escitalopram (lexapro): class

A

SSRI

44
Q

Doxepin (silenor): class

A

Tricyclic antidepressants TCA

45
Q

non depression use for imipramine

A

bed wetting

46
Q

Diazepam (Valium): class and use

A

Benzodiazipines fo anxiety

47
Q

Naltrexone (trexan, Revia): class and use

A

pure antagonist that blocks the euphoric effects of opioids

48
Q

Alprazolam (Xanax): class and use

A

Benzodiazipines fo anxiety

49
Q

Desipramine (norpramin): class

A

Tricyclic antidepressants TCA

50
Q

SE of clozapine

A

agranulocytosis and seizures

51
Q

action of mirtazapine

A

atypical antidepressant; alpha2-antagonist(inc release of Norepinephrine and 5-HT), potent 5-HT2 and 5-HT3 receptor antagonist

52
Q

Tx for social phobias

A

SSRI

53
Q

what does MAO metabolize

A

Norepinephrine, 5-HT, and dopamine

54
Q

action of trazodone

A

atypical antidepressant; inhibits 5-HT reuptake

55
Q

non depression use for duloxetine

A

diabetic peripheral neuropathy

56
Q

Tx for PTSD

A

SSRI

57
Q

Tx for bulimia

A

SSRI

58
Q

Tx for Panic disorder

A

SSRI, venlafaxine, benzo

59
Q

uses of MAOIs

A

Atypical depression, anxiety, hypochondriasis

60
Q

Clozapine: class

A

New antipsychotic

61
Q

Lorazepam (Ativan): class and use

A

Benzodiazipines fo anxiety

62
Q

Clonidine (Catapres): use

A

marketed for high BP effective somatic tx -nonaddicting

63
Q

Clomipramine (anafranil): class

A

Tricyclic antidepressants TCA

64
Q

Oxazepam (Serax): class and use

A

Benzodiazipines fo anxiety

65
Q

Entacapone (Comtan): use

A

Parkinson disease

66
Q

Sertraline (Zoloft): class

A

SSRI

67
Q

Disulfiram (antabuse): use

A

Inhibits acetaldehyde dehydrogenase that creates an unpleasant reaction when drinking alcohol which reduces the desire to drink

68
Q

High potency antipsychotics

A

Trifluoperazine, Fluphenazine, Haloperidol(Try to Fly High)

69
Q

Tx for depression with insomnia

A

mirtazapine

70
Q

low potency antipsychotics

A

Chlorpromazine, Thioridazine

71
Q

Risperidone (risperdal): class

A

New antipsychotic

72
Q

uses of trazodone

A

insomnia

73
Q

uses of bupropion

A

smoking cessation

74
Q

toxicity of MAOIs

A

hypertensive crisis

75
Q

Phenelzine (nardil): class

A

Monoamine Oxidase inhibitors

76
Q

protriptyline (Vivactal): class

A

Tricyclic antidepressants TCA

77
Q

Haloperidol (Haldol): class

A

Older Antpsychotic

78
Q

Imipramine (tofranil): class

A

Tricyclic antidepressants TCA

79
Q

Loxapine (loxitane): class

A

Older Antpsychotic

80
Q

Olanzapine (zyprexa): class

A

New antipsychotic

81
Q

action of antipsychotics

A

block dopamine D2 receptors(inc [cAMP])

82
Q

Tx for depression w/o insomnia

A

SSRI, SNRI, TCAs, buspirone, mirtazapine

83
Q

TCAs

A

end in -iptyline or -ipramine except doxepin and amoxapine

84
Q

benefit of atypical antispychotics over typical antipsychotics

A

fewer extrapyramidal and anticholinergic SEs

85
Q

Fluphenazine (prolixin): class

A

Older Antpsychotic

86
Q

Tx for cardiotoxicity assoc with TCAs

A

NaHCO3

87
Q

quetiapine (seroquel): class

A

New antipsychotic

88
Q

fluoxetine (prozac): class

A

SSRI

89
Q

Buprenorphine (Suvutex): class and use

A

suppress heroin use inpt and outpt, blocks opiioid withdrawal

90
Q

Tx for serotonin syndrome

A

cyproheptadine(5-HT2 receptor antagonist)

91
Q

fluvoxamine (luvox): class

A

SSRI

92
Q

use of buspirone

A

generalized anxiety disorder(no sedation, addiction, or tolerance)

93
Q

Mirtazipine (Remeron): class

A

Dual-acting SNRI

94
Q

Methadone (dolophine): class and use

A

a synthetic opiate that blocks the craving for and effects of herion

95
Q

Carbamazepine (Carbatol, Tegretol): class

A

Mood stabilizer

96
Q

Citalopram (celexa): class

A

SSRI

97
Q

action of maprotiline

A

atypical antidepressant; blocks norepinephrine reuptake

98
Q

Action of Buspirone

A

stimulates 5-HT1A receptors

Project - USMLE Step 3 (82 decks)

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