Psychiatry: Pharm Flashcards by Deleted Deleted

Sx of neurleptic malignant syndrome (NMS)

Fever, Encephalopathy, Vitals unstable, Elevated enzymes, Rigidity of muscle

This is remembered by the acronym FEVER.

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MAOIs

Tranylcypromine, Phenelzine, Isocarboxazid, Selegiline (selective MAO-B inhibitor)

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SE of mirtazapine

sedation, inc appetite, weight gain, dry mouth

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Halazepam (Paxipam): class and use

Benzodiazipines fo anxiety

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Tx for tourette’s syndrome

antipsychotics (haloperidol, risperidone)

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Carbidopa-levodopa (Sinemet): use

Parkinson disease

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Venlafaxine (Effexor): class

Dual-acting SNRI

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Aripiperazole (Abilify): class

New antipsychotic

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Lithium: class

Mood stabilizer

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SSRIs

Fluoxetine, Paroxetine, sertraline, Fluvoxamine, citalopram

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Mesoridazine (serentil): class

Older Antpsychotic: Low potency

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SE of chlorpromazine

corneal deposits, sedation, anticholinergic effects

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Amitriptyline (Elavil): class

Tricyclic antidepressants TCA

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Clonazepam (klonopin): class and use

Benzodiazipines fo anxiety

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Donepezil (aricept): use

acetylcholinesterase inhibitor for Alzheimer’s disease

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SE of haloperidol

neuroleptic malignant syndrome, tardive dyskinesia

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SNRIs

venlafaxine, duloxetine

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Trimipramine (Surmontil): class

Tricyclic antidepressants TCA

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atypical antipsychotics

Olanzapine, clozapine, quietiapine, risperidone, aripiprazole, ziprasidone

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action of bupropion

Atypical antidepressant that primarily acts as a mild dopamine reuptake inhibitor and a much weaker norepinephrine reuptake inhibitor as well as a nicotinic acetylcholine receptor antagonist. It does not cause weight gain or sexual dysfunction but does reduce the seizure threshold

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Tx for schizophrenia

antipsychotics

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Tx for alcohol withdrawl

benzodiazepine

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Chlordiazepoxide (Librium): class and use

Benzodiazipines fo anxiety

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SE of lithium

tremor, sedation, edema, heart block, hypothyroidism, polyuria(ADH antagonist), and teratogenesis

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Paroxetine (PAxil): class

SSRI

Tx for anxiety

SSRI, SNRI, buspirone

Tx for ADHD

methylphenidate, amphetamines

Tx for Bipolar disorder

lithium, valproic acid, carbamazepines

nortiptyline (Pamelor): class

Tricyclic antidepressants TCA

Buspirone (BuSpar): class and use

Misc drug, anxiety

drugs used to Tx fibromyalgia

TCAs

Sx of serotonin syndrome

Hyperthermia, confusion, myoclonus, CV collapse, flushing, diarrhea, seizures

Sx of tardive dyskinesia

stereotypic oral-facial movements as a result of long term antipsychotic use

SE of thioridazine

retinal deposits, QT prolongation

SE of TCAs

Convulsion, Coma, Cardiotoxicity

endocrine SE of antipsychotics

antagonism of dopamine receptor--\> hyperprolactinemia--\> galactorrhea

Valproic Aid: class

Mood stabilizer

Clorazepete (Tranxene): class and use

Benzodiazipines for anxiety

Bupropion (Wellbutrin): class

Dual-acting DNRI

Tx for NMS

Dantrolene or D2 agonist (bromocriptine)

Duloxetine (Cymbalta): class

Dual-acting SNRI

Ziprasidone (Geodon): class

New antipsychotic

Escitalopram (lexapro): class

SSRI

Doxepin (silenor): class

Tricyclic antidepressants TCA

non depression use for imipramine

bed wetting

Diazepam (Valium): class and use

Benzodiazipines fo anxiety

Naltrexone (trexan, Revia): class and use

pure antagonist that blocks the euphoric effects of opioids

Alprazolam (Xanax): class and use

Benzodiazipines fo anxiety

Desipramine (norpramin): class

Tricyclic antidepressants TCA

SE of clozapine

agranulocytosis and seizures

action of mirtazapine

atypical antidepressant; alpha2-antagonist(inc release of Norepinephrine and 5-HT), potent 5-HT2 and 5-HT3 receptor antagonist

Tx for social phobias

SSRI

what does MAO metabolize

Norepinephrine, 5-HT, and dopamine

action of trazodone

atypical antidepressant; inhibits 5-HT reuptake

non depression use for duloxetine

diabetic peripheral neuropathy

Tx for PTSD

SSRI

Tx for bulimia

SSRI

Tx for Panic disorder

SSRI, venlafaxine, benzo

uses of MAOIs

Atypical depression, anxiety, hypochondriasis

Clozapine: class

New antipsychotic

Lorazepam (Ativan): class and use

Benzodiazipines fo anxiety

Clonidine (Catapres): use

marketed for high BP effective somatic tx -nonaddicting

Clomipramine (anafranil): class

Tricyclic antidepressants TCA

Oxazepam (Serax): class and use

Benzodiazipines fo anxiety

Entacapone (Comtan): use

Parkinson disease

Sertraline (Zoloft): class

SSRI

Disulfiram (antabuse): use

Inhibits acetaldehyde dehydrogenase that creates an unpleasant reaction when drinking alcohol which reduces the desire to drink

High potency antipsychotics

Trifluoperazine, Fluphenazine, Haloperidol(Try to Fly High)

Tx for depression with insomnia

mirtazapine

low potency antipsychotics

Chlorpromazine, Thioridazine

Risperidone (risperdal): class

New antipsychotic

uses of trazodone

insomnia

uses of bupropion

smoking cessation

toxicity of MAOIs

hypertensive crisis

Phenelzine (nardil): class

Monoamine Oxidase inhibitors

protriptyline (Vivactal): class

Tricyclic antidepressants TCA

Haloperidol (Haldol): class

Older Antpsychotic

Imipramine (tofranil): class

Tricyclic antidepressants TCA

Loxapine (loxitane): class

Older Antpsychotic

Olanzapine (zyprexa): class

New antipsychotic

action of antipsychotics

block dopamine D2 receptors(inc [cAMP])

Tx for depression w/o insomnia

SSRI, SNRI, TCAs, buspirone, mirtazapine

TCAs

end in -iptyline or -ipramine except doxepin and amoxapine

benefit of atypical antispychotics over typical antipsychotics

fewer extrapyramidal and anticholinergic SEs

Fluphenazine (prolixin): class

Older Antpsychotic

Tx for cardiotoxicity assoc with TCAs

NaHCO3

quetiapine (seroquel): class

New antipsychotic

fluoxetine (prozac): class

SSRI

Buprenorphine (Suvutex): class and use

suppress heroin use inpt and outpt, blocks opiioid withdrawal

Tx for serotonin syndrome

cyproheptadine(5-HT2 receptor antagonist)

fluvoxamine (luvox): class

SSRI

use of buspirone

generalized anxiety disorder(no sedation, addiction, or tolerance)

Mirtazipine (Remeron): class

Dual-acting SNRI

Methadone (dolophine): class and use

a synthetic opiate that blocks the craving for and effects of herion

Carbamazepine (Carbatol, Tegretol): class

Mood stabilizer

Citalopram (celexa): class

SSRI

action of maprotiline

atypical antidepressant; blocks norepinephrine reuptake

Action of Buspirone

stimulates 5-HT1A receptors