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Board Review > Psych Pharm > Flashcards

Psych Pharm Flashcards

1
Q

4 psychoactive depressant drugs

A

EtOH, Opiodes, Barbiturates, Benzodiazepines

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2
Q

pt is emotional, slurs, ataxia, then coma. high serum GGT (gamma-glutamyl transferase). AST 2x the ALT.

A

Alcohol intoxication

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3
Q

pt with anxiety, tremors, seizures. when severe has autonomic hyperactivity, and DTs.

A

Alcohol withdrawal

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4
Q

Tx for DTs

A

Benzodiazepines

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5
Q

pt with euphoria, CNS and resp depression, decreased gag reflex, miosis, seizures (OD)

A

Opioid intoxication

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6
Q

opiod intoxication tx

A

Naltrexone or Naloxone

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7
Q

pt with sweating, mydriasis, piloerection, fever, rhinorhea, yawning, nausea, stomach cramps, diarrhea.

A

Opioid withdrawal

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8
Q

opioid withdrawal tx

A

long-term support, methadone, buprenorphine

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9
Q

pt with delirium and life threatening CV collapse

A

Barbiturate withdrawal

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10
Q

pt with severe respiratory depression, attending concerned bc of the narrow therapeutic window associated.

A

barbiturate intoxication

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11
Q

Pt with ataxia and minor respiratory depression. greater safety margin than barbs

A

benzodiazepine intoxication

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12
Q

competitive benzodiasepine antagonist

A

flumazenil

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13
Q

pt with sleep disturbance, depression, rebound anxiety and in severe cases, seizure.

A

benzodiazepine withdrawal.

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14
Q

acute barb intoxication management.

A

symptome management; assist resp and increase BP

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15
Q

psychoactive stimulants

A

amphetamines, cocaine, caffeine, nicotine

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16
Q

Pt with mydriasis, anorexia, paranoia, HTN, tachycardia, cardiac arrest or seizures.

A

amphetamine intoxication

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17
Q

Pt with increased diuresis, restlessness, twitching

A

caffeine tox

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18
Q

impaired judgement, mydriasis, tactile hallucinations (others), paranoia, sudden cardiac death

A

cocaine tox

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19
Q

Cocaine tox tx

A

benzodiazepines

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20
Q

pt with anhedonia, increased appetite, hypersomnolence, and existential crisis.

A

amphetamine withdrawal

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21
Q

pt with hypersomnolence, malaise, psychological craving, depression and suicidality.

A

cocaine withdrawal

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22
Q

pt with lack of concentration and headache

A

caffeine withdrawal

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23
Q

pt with irritability, anxiety, and craving.

A

nicotine withdrawal

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24
Q

treatment for nicotine withdrawal

A

bupropion/varenicline

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25
Q

hallucinogens

A

PCP, LSD, Cannabis

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26
Q

pt with belligerence, psycho, analgesia, vert and horiz nystagmus, homicidal, tachycardia, seizures

A

PCP

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27
Q

PCP tox tx

A

benzodiazepines, rapid acting anti-psychotics

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28
Q

pt with anergia, depression, anxiety, thought and sleep disturbance.

A

PCP withdrawal

29
Q

pt with perceptual distortion, depersonalization, anxiety, paranoia, psychosis, flashbacks.

A

LSD

30
Q

antiemetic in chemotherapy and stimulates apetite in AIDS.

A

dronabinol (cannabis)

31
Q

paranoid delusions, dry mouth, and conjunctival injections.

A

cannabis

32
Q

long acting oral opiate, heroin detox and long-term maintenance

A

methadone

33
Q

heroine withdrawal treatment with abuse potential

A

oral naloxone with buprenorphin

34
Q

wernicke triad

A

confusion, ophthalmoplegia, and ataxia

35
Q

irreversible memory loss, confabulation, and personality change.

A

korsakoff

36
Q

Mallory-weiss syndrome

A

longitudinal lacerations of esophagus, vomiting associated with alcoholism

37
Q

painful esophageal bleeding

A

mallory weiss as opposed to esopha varices

38
Q

DTs

A

2-5 days after last drink. ANS hyperactivity, hallucinations, confusion

39
Q

DT Tx

A

benzodiazepine

40
Q

induces vomiting from alcoholic byproduct buildup

A

disulfiram

41
Q

AnxietyTx

A

SSRIs, SNRIs, buspirone

42
Q

ADHD tx

A

methylphenidate, and amphetamines

43
Q

bipolar Tx

A

mood stabilizers: lithium, valproic acid, carbamazapine. and atypicals

44
Q

bulimia tx

A

SSRIs

45
Q

depression tx

A

SSRI, SNRI, TCA, buspirone, mirtazapine

46
Q

depression with insomnia tx

A

mirtazapine

47
Q

OCD tx

A

SSRIs, clomipramine

48
Q

panic disorder tx

A

SSRIs, venlafaxine, benzodiazepines

49
Q

PTSD Tx

A

SSRI

50
Q

schizophrenia

A

antipsychotics

51
Q

social phobias tx

A

SSRIs

52
Q

Tourrette’s Syndrome Tx

A

antipsychotics - haldol, risperidone

53
Q

3 CNS stimulants

A

Methylphenidate, dextroamphetamine, methamphetamine

54
Q

MOA of CNS stimulants and use

A

increase synaptic catecholamines - ADHD, narcolepsy, appetite control

55
Q

neuroleptics (antipsychotics) 5

A

haloperidol + -azines (trifluoperazine, fluphenazine, thioridazine, chlorpromazine)

56
Q

MOA of typical neuroleptics

A

block D2 receptors; increase cAMP

57
Q

Try to Fly High

A

in ref to high potency neuroleptics: trifluoperazine, fluphenazine, and haloperidol

58
Q

Cheating Thieves are Low

A

ref to low potency neuroleptics: Chlorpromazine and Thiaridazine

59
Q

side effects of high potency neuroleptics

A

extrapyramidal - tardive dyskinesia

60
Q

side effects of low potency neuroleptics

A

non-neurologic - alpha1 blockade, anticholinergic and antihistamine

61
Q

neuroleptic that leaves corneal deposits

A

chlorpromazine

62
Q

neuroleptic that leaves retinal deposits

A

thioridazine

63
Q

EPS evolution of effects with neuroleptics

A

4hr, days, wks, mos. acute dystonia, akathisia, bradykinesia, tardive dyskinesia.

64
Q

It’s atypical for OLd CLOSets to QUIETly RISPER from A to Z.

A

Olanzapine, Clozapine, Quetiapine, Risperidone, aripiprazole, ziprasidone

65
Q

Tx of possitive and negative symptoms of schizophrenia

A

atypical antipsychotics

66
Q

clinical use of atypical antipsychotics

A

schizo, bipolar, OCD, anxiety, depression, mania, tourettes

67
Q

atypicals associated with weight gain

A

olanzapine and clozapine

68
Q

requires weekly WBC monitoring

A

clozapine - due to agranulocytosis and seizure

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