5/21/2014 Flashcards

1
Q

subacute combined degeneration

A

degen of lat and post spinal columns - B12 deficiency, copper, or vit E deficiency.

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2
Q

MCV

A

mean corpuscular volume - average volume of red cells in a specimen

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3
Q

intracellular iron storage

A

ferritin

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4
Q

battery factories

A

lead exposure

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5
Q

shipyards

A

asbestosis

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6
Q

microcytic anemias

A

lead, thalassemias, RA

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7
Q

number of people with a genotype that express the phenotype

A

penetrance

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8
Q

varied degree of disease within the same genotype

A

variable expression

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9
Q

gag reflex

A

in by nine (glossopharyngeal) out by ten

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10
Q

hypoglossal nerve

A

XII - motor of the tongue

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11
Q

vagus afferent or efferent

A

efferent

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12
Q

pneumoconioses

A

coalworkers (anthracosis), silicosis, beryliosis, asbestosis

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13
Q

sandblasters

A

silicosis

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14
Q

aerospace industry

A

berylliosis

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15
Q

construction, plumbing, and shipyards

A

asbestosis

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16
Q

impaired phagolysosome formation by macrophages leads to increased risk of TB

A

silica

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17
Q

fibrosis of massive exposure to carbon dust

A

black lung

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18
Q

boutonniere deformaty

A

RA

19
Q

carbon dust pneumoconiosis associated with

A

RA, caplan syndrome (basilar nodules on xray in addition to coal miners RA)

20
Q

dactylitis - swelling of soft tissues between joints - interstitial fibrosis

A

sausage fingers - psoriatic arthritis

21
Q

rheumatoid nodules surrounded by pigmented cells

A

specific for caplan syndrome

22
Q

noncaseating granulomas in lungs, hilar nodes, and systemic organs.

A

sarcoidosis

23
Q

sarcoidosis with pneumoconiosis

A

berylliosis

24
Q

lung carcinoma is more common than mesothelioma in

A

asbestosis

25
Q

xerostomia

A

sjogrens

26
Q

AR low UGT activity and increased UCB under stress

A

gilbert syndrome

27
Q

absense of UGT, increased UCB - fatal in infancy

A

Crigler-Najjar

28
Q

AR deficient bilirubin canalicular transport protein, increased CB - dark liver

A

Dubin-Johnson

29
Q

dubin-johnson with no liver discoloration

A

rotor syndrome

30
Q

increase in both UCB and CB, dark urine

A

viral hep

31
Q

increased CB

A

obstructive or Dubin-Johnson

32
Q

abnormal development of 3 and 4th branchial pounches

A

digeorge

33
Q

abnormal 3rd branchial arch

A

congenital pharyngocutaneous fistula

34
Q

failure of migration of 1st branchial arch - AD

A

treacher collins

35
Q

first line treatment of acute gout - cox inhibitor and prostaglandin synthesis impeded.

A

indomethacin - NSAIDS

36
Q

block TNF, used in autoimmune diseases

A

Etanercept and Infliximab

37
Q

depolymerization of microtubules, impaired chemotaxis and degranulation - acute gout tx

A

colchicine

38
Q

xanthine oxidase inhibitor, prophylactic gout treatment

A

allopurinol

39
Q

generates acetate in mitochondria

A

acealdehyde dehydrogenase

40
Q

function of disulfiram

A

increased acetaldehyde

41
Q

aromatase inhibitor

A

anastrazole

42
Q

contraindicated in tx of breast cancer

A

estrogens

43
Q

medical abortion drug

A

mifeprestone

44
Q

medical stimulation of labor contraction and cervical dilation

A

Dinoprostone