Psych high yield Flashcards

1
Q

type of drug -

sertraline

A

SSRI

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2
Q

type of drug -

FLUOXETINE

A

SSRI

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3
Q

type of drug -

PAROXETINE

A

SSRI

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4
Q

type of drug -

CITALOPRAM

A

SSRI

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5
Q

type of drug -

ESCITALOPRAM

A

SSRI

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6
Q

type of drug -

AMITRIPTYLINE

A

TCA

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7
Q

type of drug -

LOFEPRAMINE

A

TCA

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8
Q

type of drug -

CLOMIPRAMINE

A

TCA

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9
Q

type of drug -

DOSULEPIN

A

TCA

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10
Q

type of drug -

VENLAFAXINE

A

SNRI

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11
Q

type of drug -

DULOXETINE

A

SNRI

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12
Q

type of drug -

MIRTAZAPINE

A

NASSA
noradrenaline serotonin specific antidepressant

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13
Q

type of drug -

MOCLEBEMIDE

A

MAOI
monoamine oxidase inhibitors

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14
Q

type of drug -

PHENELZINE

A

MAOI

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15
Q

type of drug -

TRAZADONE

A

SARI

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16
Q

SSRI MOA

A

block serotonin reuptake from synaptic cleft
overall reduction in inhibitory controls of serotonin release

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17
Q

SSRI main S/E

A

GI upset - abdominal pain, constipation, nausea

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18
Q

TCA MOA

A
  • block reuptake of noradrenaline
  • block reuptake of serotonin
    ^ via blocking their transporter
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19
Q

which molecules are antagonised by TCAs?

A
  • histamine
  • dopamine
  • acetylcholine
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20
Q

main TCA S/Es

A
  • sedative
  • weight gain
  • anticholinergic syndrome - dry mouth + constipation
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21
Q

MOA of SNRI

A

selectively block noradrenaline and serotonin (TCA are not selective)

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22
Q

main SNRI S/Es

A

GI upset
hypertension
palpitations

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23
Q

MOA for mirtazapine

A

presynaptic antagonism of:
- noradrenaline
- serotonin
- histamine

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24
Q

which drug blocks alpha2-adrenergic receptors, causing increase in neurotransmitter release?

A

mirtazapine

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25
Q

which drug can be used to counter S/E of SSRI?

A

mirtazapine

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26
Q

MOA of MAOI

A
  • block monoamine oxidase
  • prevents breakdown of serotonin + noradrenaline
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27
Q

reversible MAOI?

A

moclebemide

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28
Q

Irreversible MAOI

A

phenelzine

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29
Q

sodium valproate MOA

A

blocks voltage sensitive Na channels
increase in GABA level

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30
Q

lamotrigine MOA

A

blocks voltage sensitive Na channels

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31
Q

mood stabiliser causing SJS

A

lamotrigine

32
Q

MOA for typical anti-psychotics

A

block dopamine
D2 receptors

33
Q

extra-pyramidal side effects caused by?

A

typical anti-psychotics

34
Q

examples of extra-pyramidal S/Es

A

acute dystonia
akathisia
Parkinsonism
tardive dyskinesia

35
Q

muscle rigidity, feber, autonomic instability + cognitive changes - in responsive to antipsychotics (usually 1st gen)

A

neuroleptic malignant syndrome

36
Q

how can extra-pyramidal S/Es be managed

A

procyclidine

37
Q

rapid tranquillisation

A

1st - oral lorazepam

2nd - IM ^

38
Q

MOA of benzodiazepines

A

activate GABAa receptors
causes inhibition of neurotransmission
hence sedative relaxing affect

39
Q

Patient fake illness for attention, includes adding blood to urine sample etc
admitting patient makes them happy

A

Munchausens / factitious disorder

40
Q

presentation of non-euro symptoms without an obvious cause. Admission does not make them any happier

A

somatoform disorder

41
Q

presence of neurological symptoms without any cause - usually stressed pt

A

conversion disorder

42
Q

patient believes they have a serious condition and requests frequent investigations
+ high health anxiety

A

hypochondriasis

43
Q

patient shows no concern over worrying symptoms such as not being able to move a limb

A

La Belle indifference

44
Q

PTSD symptoms<1 month

A

acute stress reaction

45
Q

Delusion that someone is in love with them

A

De Clerambault’s syndrome

46
Q

delusion where you believe partner is unfaithful for no reason

A

Othello syndrome

47
Q

fixed false belief that you are dying/degrading

A

Cotard’s syndrome

48
Q

the belief that different people are the same person, but in disguise

49
Q

belief that close relative/partner has been replaced by an imposter

A

capgras delusion

50
Q

thought disorder -
no connection between ideas in succession

A

knights move thinking

51
Q

thought disorder -
many ideas rapidly in succession - maintains link

A

flight of ideas

52
Q

SSRI contraindication in elderly

A

anti-coagulant such as warfarin

53
Q

section 5(2)

A

emergency detention

54
Q

section 2

A

short term detention / assessment

55
Q

section 3

A

long term detention up to 6 months

56
Q

1st line tx for adolescent bullimia nervosa

A

Bullimia nervosa family therapy / FT-BN

57
Q

tx for acute alcohol withdrawal?

A

lorazepam / benzos

58
Q

tx for mild alcohol dependence

59
Q

management for high/at risk alcohol dependence?

A

CBT + nalmefene

60
Q
  • fever
  • muscle rigidity
  • confusion
  • rhabdo
    after dopamine antagonist?
A

neuroleptic malignant syndrome

61
Q

slow, withdrawn speech, negative symptom of schizophrenia

62
Q

S/Es of valproate?

A

alopecia
weight gain
tremor

63
Q

cardiac complication of anorexia

A

mitral valve prolapse from loss of cardiac muscle

64
Q

1st line for severe alzheimers

A

memantine / NMDA antagonist

65
Q

donepezil contraindication

66
Q
  • acute confusion
  • hallucinations
  • autonomic hyperactivity
    72hrs after alcohol
A

delirium tremens

67
Q

first line tx for delirium tremens

68
Q
  • diarrhoea
  • mydriasis (dilated pupils)
  • yawning
  • runny nose
  • goose bumps
A

opiate withdrawal

69
Q

Name that OD:
- constipaiton
- urine retention
- delirium
- dilated pupils
- dry skin

A

amytriptyline

70
Q

Drug syndrome:
- agitated
- hyperthermic
- sweating
- headache

A

serotonin syndrome:

SSRI + cocaine/ methamphetamines

71
Q

Name that OD:
- agitation
- tachy
- sweats
- hypertension
- chest pain

72
Q

tremers
sweating
agitation
6-12 hours after alcohol

A

alcohol withdrawal

73
Q

antipsychotics associated with hyperprolactinaemia?

A
  • amisulpride
  • risperidone
74
Q

treatment for extrapyramidal S/Es of dopamine agonists (ie acute dystonia)

A

procyclidine
IV Benzes

75
Q

screening for post natal depression

A

Edinburgh scale

76
Q

parksons + cog impairment vs LBD?

A

parkinsons: motor symptoms present for 1 year> cog/ memory issues