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Psych Rotation > Psych drugs (GOOD REV!) > Flashcards

Psych drugs (GOOD REV!) Flashcards

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1
Q

List the 6 typical anti-psychotics

+common suffix

A 
Haloperidol
Pimozide
Trifluoperazine
Fluphenazine
Thioridazine
Chlorpromazine
(azine/azide)

(Haloed pimps & trifling thieves flew by cheating)

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2
Q

increase cAMp

block D2 receptor

A

typical anti-psychotics

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3
Q

High potency typical antipsychotics

A

Haloperidol
Trifluoperazine
Fluphenazine

(trifling Halos flew High)

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4
Q

Low potency typical antipsychotics

A

Chlorpromazine, Thioridazine

cheating theives are low

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5
Q

List 1 atypical antipsychotic and the other’s 2 common suffix

A

Aripiprazole

(+apine)(+Peridone/ idone)

asenapine, clozapine, quetipine,

iloperidone, paliperidone, risperidone, lurasidone, ziprasidone

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6
Q

serotonin (2A) and dopamine (D2) antagonist

A

Atypical antipsychotics

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7
Q

which atypical anti-psychotic is a partial D2 agonist

A

Aripiprazole

Ari is a pipsqueak and an atypical pop-star

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8
Q

causes agranulocytosis and seizures

A

Clozapine; atypical

watch clozapine closely

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9
Q

causes hyperprolactenemia (galactorrhea, amenorrhea, man boobs/ gynecomastia)

A

Risperidone; atypical

makes me think of the ice-cream a raspado. ice-cream is milky

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10
Q

causes metabolic syndrome

weight gain, dyslipidemia, diabetes

A

Clozapine
Olanzapine
Risperidone
Quetiapine

(put a CORQ in it)

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11
Q

Antipsychotics (2)

causes a prolonged QT interval

A

Ziprasidone (less EPS)

Risperidone (more EPS)

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12
Q

For treatment resistant schizophrenia &

schizophrenia associated with Suicidality

A

Clozapine

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13
Q

Clozapine can cause:
Metabolic syndrome
agranulocytosis

and what else (2)

A

Seizures

Myocarditis (angina/dyspnea)

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14
Q

Antipsychotics (2)
Causes sedation, orthostatic hypotension, &
anticholinergic side effects (dry mouth, dilated pupils, tachycardia, constipation)

A

Chlorpromazine, Thioridazine

1st gen low potency

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15
Q

Can cause sudden onset sustained muscle contractions, Dystonia. (3)

A

Haloperidol
Trifluoperazine
Fluphenazine
(typical antipsychotics high potency)

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16
Q

Can cause Tremor, Rigidity, Blunted affect, and Bradykinesia

A

Haloperidol
Trifluoperazine
Fluphenazine
(typical antipsychotics high potency)

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17
Q

Can cause subjective restlessness with inability to sit still (Akathisia)

A

Haloperidol
Trifluoperazine
Fluphenazine
(typical antipsychotics high potency)

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18
Q

Can cause involuntary tics or choreoathetoid movements after chronic use

A

Haloperidol
Trifluoperazine
Fluphenazine
(typical antipsychotics high potency)

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19
Q

Fever, Rigidity with Hyporeflexia, mental status change, diaphoresis, Autonomic Instability
Recent use of Dopamine Antagonist

A

Neuroleptic malignant syndrome

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20
Q

Schizophrenia: excess dopamine in this pathway

A

Mesolimbic

21
Q

Fever, Clonus with Hyper-reflexia, mental status change, Hypertension, tachycardia, diaphoresis
use of SSRI, MOA-I, Dextromethorphan (cough syrup)

A

Serotonin Syndrome

22
Q

Drug-induced parkinsonism is caused by dopamine (D2) receptor blockade in the ____ pathway.

A

naigrostriatal

23
Q

Drug-induced parkinsonism can be caused by (4)

A

1st gen Antipsychotics

Antiemetics/gastric motility agents
(metoclopromide, Odansetron/ prochlorepezine)

Mood stabilizers
(Valproate, Lithium)

MPTP dmg to Substantia Nigra

24
Q

Mood stabilizer for Bipolar

Manic & Depressive features

A

Lithium

25
Q

Mood stabilizer for Bipolar

Manic features only

A

Valproate, Carbamazepine

26
Q 
Mood stabilizer for Bipolar
Depressive features (only)
A

Lamotrigene

27
Q 
Mood stabilizer with following AE:
Nephrogenic Diabetes Insipidus
Tremor
Hypothyroidism
Teratogen (Ebstein's Anomaly)
A

Lithium

28
Q

Mood stabilizer with following AE:
Hepatotoxicity
Teratogen (neural tube defects)

A

Valproate

29
Q

Mood stabilizer with following AE:
Aplastic Anemia
SIADH
Teratogen (neural tube defects)

A

Carbamezapine

30
Q

Mood stabilizer with following AE:
Benign Rash
Steven Johnson Syndrome

A

Lamotrigene

31
Q

Mirtazepine mechanism of action

A

alpha 2 anTagonist

*causes weight gain & sedation. Good for Elderly

32
Q

Which antidepressants is lethal in overdose

A

TCAs

33
Q

TCA overdose treated with

A

Sodium Bicarbonate (IV)

34
Q

Monoamine Oxidase Inhibitor mechanism of action

A

IRREVERSIBLY inhibits MAO A/B to stop the inactivation of NE, 5HT, Dopamine & Tyramine to increase their availability in the synaptic cleft.

35
Q

Enuresis treated with

A

Desmopressin (1st line)

Imipramine (TCA)

36
Q

Chronic pain/ Neuropathic pain treated with (2)

A

SNRI

TCAs

37
Q

The only ((mood stabilizer)) shown to decrease suicidality

A

Lithium

38
Q

2 mood stabilizers/ anticonvulsants that can cause Stevens Johnson Syndrome

A

Carbamazepine

Lamotrigine

39
Q

Medication helps with impulse control, but causes cognitive slowing and kidney stones

A

Topiramate

40
Q

a weak, non-competitive antagonist of the NMDA receptor, which increases dopamine release and prevents dopamine re-uptake.
Used for drug induced Parkinson’s

A

Amantadine

41
Q

A cholinesterase inhibitor used to reverse the toxic CNS effects caused by anticholinergic drugs.

A

Physostigmine

42
Q

SSRI with anticholinergic SE & weight gain

A

Paroxetine

43
Q

3 side effects of Trazadone

A

Sedation
Priapism
Orthostatic hypotension

44
Q

Which drugs go HAM

anti- Histamine, Alpha1, Muscarinic

A

TCA
1st gen Low pot. antipsychotics
Clozapine, Olanzapine, Risperidone, Quetiapine

45
Q

SSRI with the shortest half-life

A

Paroxetine (2 weeks or less)

46
Q

Suvorexant is an ____ inhibitor

A

orexin

insomnia

47
Q

What is the Black Box warning for antipsychotics?

A

Increased Mortality in pts w/ Dementia

still used, but 2nd gen like Quetiapine

48
Q

Competitive inhibition of histamine at H2 receptors of the gastric parietal cells, which inhibits gastric acid secretion

A

Famotidine
(GERD)

*watch for delirium in elderly

Psych Rotation (7 decks)

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