Last minute things Flashcards
Self- harm (cutting) may indicate what
Borderline Personality disorder
In OCD thoughts must be recurrent & time consuming (≥1hr), \_\_\_\_, OR \_\_\_\_
distressing
impairing
Impressionable, considers relationships more intimate than they are, inappropriate sexual/seductive behavior, uses appearance to draw attention, dramatic displays of emotion
Histrionic
Blames others for mistakes
Deliberately annoys others
Short tempered, irritable, argumentative, defiant, OR vindictive
Oppositional Defiant
≥6m
ODD and Conduct disorder treated with
Parent Management Training
Psychotherapy & CBT, respectively
Dissociative amnesia/fugue triggered by
an emotionally stressful event
The depressive and hypomanic episodes in bipolar II disorder may resemble borderline personality disorder. However, the labile mood states in borderline personality disorder are
brief, typically lasting hours to days (rather than weeks to months).
and come with other Borderline symptoms
Insecure attachment to the primary caregiver may underlie the unstable relationships and fears of abandonment commonly seen in the disorder.
Borderline Personality disorder
Poor social responsiveness, limited affect, does not seek/respond to comfort, unexplained irritability/sadness/ fear, +/- toileting problems, anxiety, aggression, sleep problems
Reactive Attachment Disorder
Describe delusional disorder
time frame
Treatment
≥1 delusion
≥1 month
no functional impairment
Antipsychotic or CBT
Hoarding → treat with
CBT, if persistent use SSRI (off label)
OCPD obsessed with
Details, Control, Perfectionism
NO Rituals/Compulsions
NO Feared thoughts
Fear of Scrutiny and embarrassment
SAD
GAD causes significant distress or impairment due to chronic worries ≤6m
Must have 3+ of the following symptoms (7)
Fatigue impaired concentration irritability Tension (muscles) On edge Restless Sleep disturbances
FiiTORS
Panic disorder has ≥4 of the following symptoms (15)
SOB Trembling Upset stomach Dizziness Derealization/Depersonalization Numbness Tingly/Paresthesia Sweating Palpitations Avoidance behaviors Nausea Intense Fear of dying Chest pain/Choking
STUDDNTS PANIC
Symptoms of PTSD (9)
Flashbacks Irritability Nightmares Negative mood Dissociation Avoidance (of reminders) Amnesia (of event) Hyper-vigilance
FINNDAAH
First-line treatment of specific phobia
Exposure therapy & CBT
Benzos for acute settings
Is conversion disorder intentional?
No
1st line treatment for conversion disorder
Pt education/self-help
(2nd line) CBT
List all the things that can cause Serotonin Syndrome
10
SSRI SNRI TCA MAO-I Tramadol Linezolid Dextromethorphan MDMA Ondansetron Meperidine (opioid for acute pain)
Treatment of Genito-pelvic pain disorder
Desensitization therapy
Kegel pelvic floor exercises
5HT-1A partial agonist. Inhibits serotonin reuptake
Vilazodone
atypical antidepressant
5HT-1A agonist.
5HT-3 antagonist.
Inhibits serotonin reuptake
Vortioxetine
atypical antidepressant
Indications for ECT (5)
Treatment Resistance MMD w/Psychotic features Pregnancy Refusal to eat/drink Suicidal
List 3 protective factors for suicide
Pregnancy
Parenthood
Religion
Social/family support
Depressed new mother for:
__ weeks → Blues
__ weeks → MDD
≤2 (reassurance)
≤ 2 (CBT + SSRI)
Adjustment disorder treatment
Psychotherapy
w/ adjunctive sleep aid like Zolpidem or anxiolytic if needed.
Peripheral alpha 1 antagonism causes
vasodilation (orthostatic hypotension)
Discontinuation of SSRI may cause
Flu like Insomnia Nausea/Vomit/Diarrhea Instability (Dizziness) Sore muscles (myalgias) Headache
Treatment of lithium toxicity (2)
IV hydration
Dialysis (if severe)
4 contraindications for Lithium
CKD
Heart disease
Hyponatremia
Diuretic use
Lithium may cause
Polyuria/Polydipsia
List 7 psychiatric medical emergencies
NMS Serotonin Syndrome TCA overdose Tyramine HTN crisis Acute Dystonia Delirium Tremens Lithium Toxicities
Patient with Parkinson or DLB can be given what antipsychotic?
Qutiapine (which binds D2 loosely)
or
Pimvaserin
Antipsychotics causing orthostatic hypotension like _______ not good for elderly. Not good at all for parkinsonism.
Risperidone
but still can be used
Low potency typicals do not
bind D2 very tightly
2nd Gen antipsychotics can cause weight gain and (2)
Dyslipidemia
Hyperglycemia
(monitor lipids & A1C)
Which antipsychotic causes
Metabolic syndromes/weight gain
EPS &
Prolonged Qtc
Risperidone
Which 2 antipsychotics cause Prolonged Qtc
Risperidone
Ziprasidone
List 3 overlapping features of NMS & SS
Fever
Autonomic Instability (sweats, tachycardia, HTN)
Mental status altered
(FAM)
NMS: muscle rigidity
SS: Myoclonus/hyper-reflexia
Schizophrenia must have 1 of the following 3 symptoms:
&
have either of the following 3 symptoms:
Hallucinations, Delusions, Disorganized speech
Negative symptoms, Bizarre behavior, Catatonia
What are the 5 As of negative symptoms in Schizophrenia?
Alogia (brief answers/ speaking little) Anhedonia Affect (flat) Avolition (apathy) Attention (poor)
In Wilson’s disease the Basal Ganglia gets deposits of copper. Neurologic findings can include (4)
& come before obvious hepatic symptoms in teenagers with acute psychosis.
dysarthria
dystonia
tremor
pooling saliva
Patient has overdosed on Heroin and has a RR<8 what do you do next?
Intubate then give IM Naloxone
With opioid intoxication what do you expect to find in ABG and finger glucose stick?
Respiratory Acidosis
Hypoglycemia
What is a normal pupil size?
Normal Pupils in
LIGHT (2-4mm)
DARK (4-8mm)
Pupils <1mm = intoxication
What are some opioid withdrawal symptoms you can ask (8)
Stomach Cramps Diarrhea Piloerection Insomnia Yawning Rhinorrhea Lacrimation Muscle/joint aches
What can you give for opioid withdrawal diarrhea
Loperamide
List 3 complications of cocaine use
Myocardial ischemia or MI
Aortic Dissection
Intracranial Hemorrhage
Beta 1 stimulation causes cardiac
contractility increase
Alpha 1 stimulation causes peripheral
vasoconstriction (HTN)
Beta 2 stimulation causes bronchial ____
& peripheral _____
Dilation
Vasodilation
Why are Beta Blockers contraindicated in cocaine use?
Cocaine stimulates Alpha 1 vasoconstriction & Beta 2 vasodilation and blocking B1 & B2 will lower the heart contractility and the vasodilation of B2 but leave the alpha 1 vasoconstriction unopposed causing a HTN crisis possibly.
Alcohol withdrawal seizures &/or Hallucinosis occurs when
within 12 hours to 2 days
Delirium tremens occurs when
2-4 days
after last drink
Alcohol withdrawal shakes, anxiety, insomnia, and GI upset occur when
6 hours to 1 day
after last drink
skin picking, teeth grinding and dental decay indicate what use disorder
Meth
Methadone opioid intoxication can be caused by
Cimetidine (for GERD)
Fluconazole etc. (fungal infection)
Clarithromycin (antibiotic
Fluvoxamine (SSRI)
WHAT OUT for these CYP P450 inhibitors increasing Methadone levels in the body
Non-selective (O-Z) Beta Blockers can cause what sexual symptom?
erectile dysfunction
Anticholinergic toxicity can cause (5)
Mydriasis (blind as a bat) Tachycardia (fast as a fiddle) Dry skin/mucous memb. (Dry as a bone) Flushing (red as a beet) Urinary retention (full as a flask) Delirium (mad as a hatter) Treat with Physostigmine
Marijuana causes dry mouth, red eyes and what cardio effect?
Tachycardia
List the Neuroleptic Malignant Syndrome mnemonic
M-FEVER
Myoglobinuria (RBCs on UA) Fever Elevated Enzymes (CK & leukocytosis) Vital Unstable Encephalopathy (Delirium) Rigidity lead pipe
Meperidine (opioid) + MOI can cause
Serotonin Syndrome
Meperidine (opioid) Triptans (migraines) Ondansetron (anti-emetic) Dextromethorphan (cough syrup) MDMA (Ecstasy/ Molly) Tramadol (analgesic) MAOI TCAs/SNRIs/SSRIs
can be combined to cause
Serotonin Syndrome
Slow wave sleep is what phase
N3
N3 slow wave sleep is characterized by what waves, frequency, and amplitude?
Delta (low frequency, high amplitude)
Sleep apnea may cause an increase in what hormone?
EPO (erythropoiesis; high RBC count)
What 2 lab findings are seen in Bulimia
Hypokalemia Metabolic Alkalosis (High bicarb)
How to tell apart
NPH vs
Alzheimer’s MSA
MUD DUM
Motor > Urinary> Dementia = NPH
Dementia > Urinary > Motor = MSA
Tetrabenazine (for Tourette’s) is a
dopamine depleter
List the OARS technique for motivational interviewing
Open ended questions
Affirmation of Positives
Reflect on how it might feel in the Positive
Summarize
Fragile X Syndrome is often associated with what learning/psych problems?
Intellectual disability
ADHD
Autism
Anxiety
Self- injurious behavior is associated with what 2 congenital illnesses?
Fragile X
Lesch Nyan
Long face
Protruding ears
Hypermobility of joints
intellectual/developmental delay
Fragile X
In Alzheimer’s what neurotransmittor is affected
↓ ACH
In parkinson what neurotransmittor(s) are affected
↑ ACH
↓ Dopamine
↓ Serotonin
In Anxiety what neurotransmittor(s) are affected
↓ Serotonin
↓ GABA
↑ NE
In Huntington what neurotransmittor(s) are affected
↓ ACH
↓ GABA
↑ Dopamine
What is a U-wave on ECG?
A little hill after T wave (the last wave in 1 ECG cycle)
Lithium causes what 2 possible changes on ECG
due to HYPOKALEMIA?
U waves (after T wave) Flat/upside down T waves
List 5 MOAI
Tranyl-cypro-mine Rasagiline Isocarboxazid Phenelzine Selegiline (TRIPS)
List 6 TCAs
Amoxapin Desipramine Amyltriptyline Nortriptyline Doxepin Imipramine (A DANDI) *Timipramine
List 5 SNRIs
Desvenlafaxine Levomilnacipran Duloxetine Milnacipran Venlafaxine (Don't Lose DMV)
List 3 Antiemetics
Metoclopramide 5HT3 & D2 antagonist
Ondansetron (Zofran) 5HT3 antagonist
Prochlorperazine (Compazine) D2 antagonist
(MOP vomit)
Absent DTRs
+ Romberg
Ataxia
Shooting pain
tertiary syphilis
Enuresis/Encopresis can be associated with what 3 psychiatric conditions?
Autism
ADHD
Conduct Disorder
Triptans (anti-migraine meds) can cause
Serotonin Syndrome
Phenobarbital is a ____ acting barbituate
Long
*so is Barbitone/Mephobarbitone
PENTObarbital is a ____ acting barbituate
Medium
Thiopental is a ____ acting barbituate
Short
Huntington chorea/ tardive dyskinesia can be treated with
Tetrabenazine (for Tourettes too)
VMAT-I for ↓ Dopamine release
Alzheimers progression can be hindered with what drugs
Ach-Esterase Inhibitors
(Donepezil, Rivastigmine, Galantamine)
NMDA receptor antagonist (Ca2+ excitotox)
(Memantine)
*Of note: Amantadine is a weak, non-competitive NMDA receptor antagonist for DI-Parkinsonism
Trihexyphenidyl is used for
DI-Parkinsonism
*same MOA as Benzotropine (antimuscarinic curbs excess cholinergic activity in parkinson)
For treatment of Parkinson disease first line is ____ or ____
carbidopa-levodopa
or (or as adjunctive)
Dopamine receptor agonist (Pramipexole/Ropinirole/Bromocriptine 3rd choice)
*If it doesn’t respond to one it won’t respond to the other option.
Other second line treatments for Parkinson disease
are (
*(aside from carbidopa-levodopa & Dopamine receptor agonist )
COMT inhibitors (Encapone/Talcopone) + Carbi/Levo NMDA antagonist (Amantadine - for Akinesia) MAO-B Inhibitors (Rasagiline, Selegiline) + Carbi/Levo