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NURSING > PSYCH: DEPRESSION MEDS > Flashcards

PSYCH: DEPRESSION MEDS Flashcards

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1
Q

What medication is the gold standard for depression?

A

SSRI

Makes more serotonin available at the synapse

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2
Q

Side Effects of SSRI’s

A

GI upset
Fatigue
Dry Mouth
Decreased libido

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3
Q

What happens if an SSRI is abruptly discontinued?

A

Can develop SSRI Discontinuation Syndrome

Pt will feel like they have the flu

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4
Q 
Celexa (citalopram)
Lexapro (escitalopram)
Prozac (fluoxetine)
Luvox (fluvoxamine)
Paxil (paroxetine)
Zoloft (sertraline)
A

SSRI’s

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5
Q

What is the feel good neurotransmitter?

A

Serotonin

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6
Q

Serotonin Syndrome

A

Accumulation of Serotonin
Usually caused by a combination of substances
Everything is elevated, may be fatal

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7
Q

What combination can cause Serotonin Syndrome?

A

SSRI + MAOI
SSRI + ecstasy
St. John’s Wart

Patients need weeks between SSRI’s and MAOI’s or St.John’s Wart

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8
Q

What are the initial symptoms of Serotonin Syndrome? What might it progress to?

A

Initial symptoms: MS changes (restless/agitated), lethargy, flushing, confusion, tremors, diaphoresis, and ataxia

May progress to: hyperthermia, renal failure, hypertonicity, seizure, may be FATAL

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9
Q

SNRI

A

dual action on serotonin and norepinephrine

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10
Q

Possible side effects of SNRI’s

A

Cardiovascular risk
NV
Weight gain
Somatic symptoms (body ache)

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11
Q

Effexor XR (venlafaxine)
Cymbalta (fluoxetine)
Pristiq (desvenlafaxine)

A

SNRI’s

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12
Q

Side effects of Cymbalta?

A

Constipation
Headache
Nausea

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13
Q

What SNRI is good for body aches?

A

Cymbalta

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14
Q

Which SNRI has less sexual dysfunction?

A

Pristiq

single dose

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15
Q

NDRIs

A

Norepi and Dopamine Reuptake Inhibitors

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16
Q 
Wellbutrin
Wellbutrin XL (bupropion)
A

NDRI

No weight gain
Nausea and headache
Few sexual side effects

17
Q

Wellbutrin is also commonly used for ______ ?

A

Smoking Cessation

18
Q

A major risk factor of Wellbutrin is …

A

Decreased Seizure Threshold

19
Q

Serotonin Antagonist & Reuptake Inhibitors

A

addresses the sleep and appetite more than anything

20
Q

Serzone (nefazadone) - hepatotoxicity
**Deseryl (trazedone) - powder doses for sleep only or augmentation (give at night)
Oleptro (pt may feel hungover)
** Remeron (mirtazapine) - helps sleep & appetite (causes weight gain)

A

SARI’s

21
Q

This type of medication can have an anticholinergic effect

A

TCA

22
Q

What is an anticholinergic effect? What population is at greatest risk?

A 
DRY
Elderly (possible orthostatic HTN and increased risk for dysrhythmia)
23
Q 
Elavil (amitriptyline)
Sinequan (doxepin)
Silenor (newer doxepin)
Tofranil (imipramine)
Anafranil (clomipramine)
A

TCA’s

24
Q

MAOI

A

Contraindicated with many things and not given often

25
Q

What is contraindicated with MAOI’s

A

Nothing containing tyramine
No aged food
No fermented foods
No OTC meds (not even a little bit)

26
Q

What could potentially happen if a person taking an MAOI eats food containing tyramine

A 
HTN crisis (1st sign is headache commonly in back of head)
Can cause stroke
27
Q

Nardil (heneizine)
Parnate (tranlcypromine)
Marplan (isocarboxacid)
Emsam (selegiline) transdermal patch

A

MAOI’s

28
Q

Atypical Antipsychotics

A

Not first generation and used for depression

Used for augmentation (helps to rapidly control sx)

29
Q

Atypical Antipsychotics are most commonly used to tx ….

A

Schizophrenia

30
Q

This medication is given in low doses to rapidly control symptoms of severe depression

A

Atypical Antipsychotics

31
Q

Zyprexa
Seroquel
Abilify

A

Atypical Antipsychotics

32
Q

Zyprexa and Seroquel carry a risk for …

A

Metabolic Syndrome (fat gain; ex: fatty liver)

NURSING (16 decks)

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