MED SURG II: RENAL + NEURO Flashcards
Patchy destruction of tubular epithelium of the kidney caused by ischemia, nephrotoxins, or sepsis
Acute Tubular Necrosis (ATN)
Accumlation of urea nitrogen & creatinine (nitrogenous wastes) in the blood
Azotemia
Reduction in UOP to less than 400mL/day
Oliguria
NO urine, less than 100mL/day
Anuria
Production of abnormally large volumes of dilute urine
Polyuria
Clinical syndrome associated with fluid, electrolyte, hormone imbalances & metabolic abnormalities all caused by the kidneys
Uremia
Rapid loss of renal function
Possibly reversible
Ranges from slight deterioration in kidney function to complete impairment
Oliguria
Acute Renal Failure/ Acute Renal Injury
How is ARF diagnosed?
Sudden decrease in UOP (<400mL)
Sudden increase in Creatinine
Either or both
Pre Renal, Intra Renal, or Post Renal:
Hypovolemia
Decreased CO
Decreased PVR
Pre Renal
Pre Renal, Intra Renal, Post Renal: Prolonged pre-renal ischemia Severe Shock Damage from Nephrotoxic Drugs Antibiotics Benzos Loop diuretics Statins ACE Inhibitors ARBs Tylenol and NSAIDS Weakend or Hardened Blood Vessels Infections ATN Lupus
Intra Renal
Pre-Renal, Intra-Renal, Post-Renal: Tumors Strictures Stones BPH
Post-Renal
Pre-Renal
Reduced blood flow to the kidneys
Intra-Renal
Direct damage to renal tissue
Post-Renal
Obstruction of urinary outflow
Decreased UOP Renal function decreases Fluid retention Hypo or Hypernatremia Hyperkalemia Decreased H/H Increased BUN and Creat
1st phase of ARF: Oliguric