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Pharm > Psych > Flashcards

Psych Flashcards

0
Q

Trifluoperazine

A

High potency typical antipsychotic
Blocks dopamine D2 receptors
EPS side effects (treat benztropine or diphenhydramine)

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1
Q

Haloperidol

A

High potency typical antipsychotic
Blocks dopamine D2 receptors
EPS side effects (treat benztropine or diphenhydramine)

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2
Q

Fluphenazine

A

High potency typical antipsychotic
Blocks dopamine D2 receptors
EPS side effects (treat benztropine or diphenhydramine)

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3
Q

Chlorpromazine

A

Low potency typical antipsychotic
Blocks dopamine D2 receptors
Anticholinergic, antihistamine, a1 blockade side effects
Corneal deposits

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4
Q

Thioridazine

A

Low potency typical antipsychotic
Blocks dopamine D2 receptors
Anticholinergic, antihistamine, a1 blockade side effects
Retinal deposits

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5
Q

Olanzapine

A

Atypical antipsychotic

Weight gain

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6
Q

Clozapine

A

Atypical antipsychotic
Agranulocytosis- check CBC weekly
Weight gain
Acts on D4 receptors

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7
Q

Quetiapine

A

Atypical antipsychotic

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8
Q

Risperidone

A

Atypical antipsychotic

Prolactin increase- menstruation problems

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9
Q

Aripiprazole

A

Atypical antipsychotic

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10
Q

Ziprasidone

A

Atypical antipsychotic

Prolong qt interval

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11
Q

Lithium

A

May inhibit phosphoinositol pathway
Mood stabilizer for bipolar also SIADH
Tremor, Nephrogenic DI (and accumulate), hypothyroid (weight gain, hair loss, consto), fetal defects (Epstein anomaly and great vessel malformation)
Narrow therapeutic window

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12
Q

Buspirone

A

Stimulated 5-HT1A receptors
Generalized anxiety disorder
No interaction w etoh (unlike benzos and barbs)

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13
Q

Fluoxetine

A

SSRI
Depression, GAD, panic disorder, OCD, bulimia, PTSD, social phobias
Takes 4-8 weeks to work
Sex dysfunction
Serotonin syndrome (treat cyproheptadine)

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14
Q

Paroxetine

A

SSRI
Depression, GAD, panic disorder, OCD, bulimia, PTSD, social phobias
Takes 4-8 weeks to work
Sex dysfunction
Serotonin syndrome (treat cyproheptadine)

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15
Q

Sertraline

A

SSRI
Depression, GAD, panic disorder, OCD, bulimia, PTSD, social phobias
Takes 4-8 weeks to work
Sex dysfunction
Serotonin syndrome (treat cyproheptadine)

16
Q

Citalopram

A

SSRI
Depression, GAD, panic disorder, OCD, bulimia, PTSD, social phobias
Takes 4-8 weeks to work
Sex dysfunction
Serotonin syndrome (treat cyproheptadine)

17
Q

Venlafaxine

A

SNRI- serotonin and norepinephrine
Depression
GAD and panic disorders
Increased BP

18
Q

Duloxetine

A

SNRI- serotonin and norepinephrine
Depression
Also for Peripheral diabetic neuropathy
Increased BP

19
Q

Amytriptyline

A

TCA
Block serotonin and norepinephrine reuptake
Major depression
3* TCA more anticholinergic effects- tachy, dry mouth, urinary retention
Convulsion coma cardiotoxicity (3 Cs)
Prolonged qrs and qt
Confusion in elderly, use nortriptyline

20
Q

Nortriptyline

A 
TCA
Block serotonin and norepinephrine reuptake
Major depression, fibromyalgia
2* TCA
Convulsion coma cardiotoxicity (3 Cs)
Prolonged qrs and qt
Confusion in elderly, use nortriptyline
21
Q

-pramine

A 
TCA
Block serotonin and norepinephrine reuptake
Major depression fibromyalgia
Convulsion coma cardiotoxicity (3 Cs)
Prolonged qrs and qt
Confusion in elderly, use nortriptyline
Clomipramine for OCD
Desipramine can cause seizures
22
Q

Tranylcypromine

A

Mao-I
Increased amine NTs (NE, serotonin, dopamine)
Atypical depression, anxiety, hypochondriasis
Hypertensive crisis when eat tyramine
Cns stimulation
Contraindicated w ssri, TCA, St. John wart, meperidine, dextromethorophan because of serotonin syndrome

23
Q

Phenelzine

A

Mao-I
Increased amine NTs (NE, serotonin, dopamine)
Atypical depression, anxiety, hypochondriasis
Hypertensive crisis when eat tyramine
Cns stimulation
Contraindicated w ssri, TCA, St. John wart, meperidine, dextromethorophan because of serotonin syndrome

24
Q

Isocarboxazid

A

Mao-I
Increased amine NTs (NE, serotonin, dopamine)
Atypical depression, anxiety, hypochondriasis
Hypertensive crisis when eat tyramine
Cns stimulation
Contraindicated w ssri, TCA, St. John wart, meperidine, dextromethorophan because of serotonin syndrome

25
Q

Segeline

A

Mao-I selective MAO B
Increased amine NTs (NE, serotonin, dopamine)
Atypical depression, anxiety, hypochondriasis
Hypertensive crisis when eat tyramine
Cns stimulation
Contraindicated w ssri, TCA, St. John wart, meperidine, dextromethorophan because of serotonin syndrome

26
Q

Bupropion

A 
Atypical antidepressant
Increase NE and dopa
Also used for smoking cessation
Seizure in bulimic patients
No sexual side effects
27
Q

Mirtazipine

A

a2 antagonist (release NE and serotonin)
Potent 5-HT2 and 5-HT3 receptor antagonist
Sedation, weight gain, dry mouth

28
Q

Trazodone

A

Blocks 5-HT2 and a1- adrenergic receptors
Mostly used for insomnia
Priapism and nausea

Pharm (12 decks)

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