Adverse Effects In Pregnancy Flashcards

0
Q

Aminoglycosides

A

Ototoxicity

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1
Q

Sulfonamides

A

Kernicterus

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2
Q

Fluoroquinolones

A

Cartilage damage

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3
Q

Clarithromycin

A

Embryotoxic

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4
Q

Tetracyclines

A

Discolored teeth, inhibition of bone growth

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5
Q

Ribavirin

A

Teratogenic

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6
Q

Griseofulvin

A

Teratogenic

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7
Q

Chloramphenicol

A

Grey baby

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8
Q

Ace inhibitors

A

Renal damage

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9
Q

Alkylating agents

A

Absence of digits, others

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10
Q

Carbamazepine

A

Neural tube defects, craniofacial defects, fingernail hypoplasia, IUGR

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11
Q

Diethylstilbestrol

A

Vaginal clear cell adenocarcinoma, congenital mullerian anomalies

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12
Q

Lithium

A

Ebstein anomaly- atrialized right ventricle

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13
Q

Methimazole

A

Aplasia cutis congenita

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14
Q

Phenytoin

A

Fetal hydantoin syndrome: microcephaly, dysmorphic craniofacial features, hypoplastic nails and distal phalanges, cardiac defects, IUGR, retardation

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15
Q

Thalidomide

A

“Tha-limb-domide”

Flipper limbs

16
Q

Valproate

A

Folate antagonist

17
Q

Warfarin

A

Bone deformities, fetal hemorrhage, abortion, opthalmologic abnormalities