psych Flashcards
treatment for schizophrenia and tourettes
antipsychotics
trifluoperazine, fluphenazine, haloperidol
high potency antipsychotics - dyskinesia
chlorpromazine, thioridazine
low potency antipsychotics - anticholinergic and sedative effects
rigidity, myoglobinuria, hyperpyrexia
neuroleptic malignant syndrome - typical antipsychotics
tx: dantrolene
oral-facial movements - lip smacking
tardive dyskinesia - typical antipsychotics
block D2 receptors , inc cAMP
typical antipsychotics
olanzipine, clozapine, quetiapine, risperidone, aripiprazole, ziprasidone
atypical antipsychotics
Fewer side effects compared to typical antipsychotics
clozapine side effect
agranulocytosis
ebstein anomaly - tricuspid valve is displaced into ventricle
lithium
used for anxiety, doesn’t cause sedation, addiction or tolerance, does not interact with alcohol, long onset of action
buspirone
fluoxetine, paroxetine, sertraline, citalopram
SSRIs (Sheep FLOX PARalyze SEnior CITizens)
SE include: sexual dysfunction, hyperthermia, confusion, myoclonus, flushing, diarrhea, seizures
SSRIs
inc QT prolongation
citalopram
venlafaxine, duloxetine
SNRI
amitriptyline, nortriptyline, imipramine, clomiprimine, doxepin, amoxapine
TCAs
block reuptake of NE and serotonin
TCAs
used for bedwetting
imipramine
causes sedation, postural hypotension, tachycardia, urinary retention, dry mouth
TCAs
convulsions, coma, cardiotoxicity (arrhythmias), confusion in the elderly
TCAs
Phenelzine, tranylcypromine, isocarboxazid, selegiline
MAOI - inc NE, serotonin, dopamine
hypertensive crisis with ingestion of tyramine
MAOIs
must wait 2 weeks (wash out) before prescribing new drugs
MAOIs - need to give time for MAO to be made
inc NE and dopamine, smoking cessation
bupropion
alpha-2 antagonist (inc NE and serotonin) and 5-HT2/3 antagonist
mirtazapine
sedation, weight gain, good for elderly
mirtazapine
inhibits serotonin reuptake, used for insomnia, priapism
trazadone
