Psoriasis Flashcards
1
Q
causes of psoriasis
A
- genetics (Th1 and Th17 stimulation keratinocyte proliferation, AMP release and neutrophil-attracting chemokines)
- environmental factors e.g. stress, drugs, infection
2
Q
presentation of psoriasis
A
- plaques
- symmetrical
- extensor sites e.g. scalp, sacrum
- nail changes
- systemic diseases
3
Q
hallmark of psorasis
A
chronic, demarcated, bilateral scaly, erythematous plaques
4
Q
nail changes that can occur in psoriasis
A
onycholysis: lifting from the nail-bed
nail pitting
dystrophy
subungual hyperkeratosis
5
Q
describe Koebner’s phenomenon
A
development of psoriasis in areas of previous trauma
6
Q
systemic diseases that can occur alongside psoriasis
A
arthritis
metabolic syndromes
Crohn’s
cancer
7
Q
diagnosis
A
auspitz sign- removal of surface scale reveals tiny bleeding points
8
Q
types of psoriasis
A
- vulgaris
- guttate (everywhere)
- palmoplantar pustular
- erythrodermic
9
Q
management of psoriasis
A
- vitamin D analogues
- coal tar (use everywhere)
- dithranol
- steroid ointment (combination)
- emollients
- phototherapy
- systemic treatments e.g. methotrexate
10
Q
examples of vitamin D analogues
A
calcipotriol (localised plaques)
calcitriol (flexures)
11
Q
when is dithranol used?
A
few localised plaques, short contact
