Acne Vulgaris Flashcards

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1
Q

define acne vulgaris

A

chronic inflammatory disease of the pilosebaceous unit

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2
Q

causes of acne

A

increased androgens at puberty

genetics

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3
Q

how are comedomes formed?

A

keratin plugging of pilosebaceous unit (poral occlusion) and build-up of sebum to form comedomes

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4
Q

infection

A

colonisation by anaerobic bacteria leads to an infection with corynebacterium

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5
Q

presentation of acne vulgaris

A
  • located on face, upper back and anterior chest
  • comedones (whiteheads-closed, blackheads-open)
  • pustules
  • papules
  • cysts
  • erythema
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6
Q

secondary features in the presentation fo acne

A

scars (atrophic, ice-pick)
texture changes
hypertrophy

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7
Q

management of acne

A
  • avoid oily substances and triggers
  • topical treatments
  • systemic treatments
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8
Q

examples of topical treatments

A
  • benzoyl peroxide (keratolytic and antibacterial)
  • vitamin A derivatives (retinoids- drying effect)
  • topical antibiotics
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9
Q

examples of systemic treatments

A
oral antibiotics
oral retinoids (isotretinoin-BEWARE)
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