Psoriasis Flashcards

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1
Q

Example of a strong steroid

A

bethamethasone - betnovate

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2
Q

Features of psoriasis presentation

A

Scaley, silvery white plaques which may be mildly to severely itchy. In severe itching the skin may develop painful cracks and fissures

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3
Q

Nail psoriasis is associated with…

A

inflammatory arthritis

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4
Q

Commonly associated with flexural psoriasis?

A

candida infections

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5
Q

Nail psoriasis presents as…

A

pitting, onycholysis, yellowing and ridging

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6
Q

Example of a mild steroid

A

hydrocortisone 1%

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7
Q

Histology showing which skin disease

A

Psoriasis

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8
Q

Why would oral steroids not be used in severe psoriasis?

A

may cause rebound flare up when steroids are stopped.

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9
Q

Where is palmoplanter psoriasis found?

A

palms and soles of the feet - may cause painful fissuring

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10
Q

Most common locations for psoriasis

A

knees, elbows, scalp

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11
Q

Condition seen here

A

Psoriasis

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12
Q

Example of anti-TNF agents

A

infliximab, etanercept

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13
Q

In more extensive/severe psoriasis, what other treatments might be used?

A

UVB phototherapy, methotrexate, azathioprine, 6-mecaptopurine, biologics

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14
Q

Conditions associated with psoriasis (6)

A

inflammatory arthritis; spondyloarthropathy; IBD; Uveitis; Coeliac disease; Metabolic syndrome

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15
Q

Description of psoriasis

A

chronic, inflammatory skin condition with well-defined red and scaly plaques on the extensor surfaces

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16
Q

Key immune factors in psoriasis

A

Th17, IL-1b, TNFa

17
Q

Acute form of psoriasis

A

Guttate

18
Q

Associated with streptococcal infections

A

guttate psoriasis

19
Q

Example of a very potent steroid

A

demovate

20
Q

Key disease process in psoriasis

A

epidermal hyperplasia

21
Q

What is the Koebner phenomenon?

A

new psoriatic lesions form in areas of cutaneous injury but otherwise healthy tissue; often linear in shape and not found where psoriasis may normally be found

22
Q

Onycholysis is…

A

painless separation of the nail from the nail bed often starting at the tip

23
Q

Presentation of guttate psoriasis…

A

widespread small plaques

24
Q

Guttate psoriasis is commonly associated with…

A

streptococcal infections

25
Q

Topical treatments for mild/moderate psoriasis (6)

A

coal tar, emollients, calcipotriol, steroids, calcineurin inhibitor, salicylic acid

26
Q

Peak onset for psoriasis (2)

A

15-25years; 50-60 years

27
Q

Clinical sign seen here

A

Onycholysis

28
Q

Example of a moderate steroid

A

eumovate

29
Q

Where would flexural psoriasis commonly be found?

A

in the body folds and around the genitals

30
Q

General advice for psoriasis

A

stop smoking and drinking, maintain a healthy weight