Eczema and Dermatitis Flashcards
Investigation for allergic contact dermatitis?
patch testing
Distribution of atopic eczema in older children and adults
flexural surfaces
What is this condition?
Contact allergic dermatitis
Common infections associated with eczema? (2)
staph. aureus; herpes simplex virus
Difference between contact allergic and irritant dermatitis
Irritant does not require prior exposure and may occur due to milder irritants
T cells affected in eczema
Th2
Clues that allergic contact dermatitis may be workplace associated?
clears up on holiday
More extreme treatment of eczema
phototherapy, immunosuppressants and biologic agents
Appearance of eczema herpeticum
monomorphic punched out lesions
Condition where eczema and herpes simplex virus are combined
eczema herpeticum
Pathogenic mechanism behind allergic contact dermatitis
langherhans cells process and present the antigen at the regional lymph nodes and activate naive CD4 T cells. This results in the production of effector and memory T cells which produce a response to future exposures within 48-96 hours.
Atopic eczema is associated with what other diseases? (3)
asthma, allergic rhinitis, food allergy
Example of emollients
Diprobase, Dermol, Epaderm, E45
Appearance of skin in a person with eczema
dry, erythematous, scaling, lichenification, excoriations
Allergic contact dermatitis requires…?
prior exposure