Eczema and Dermatitis Flashcards

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1
Q

Investigation for allergic contact dermatitis?

A

patch testing

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2
Q

Distribution of atopic eczema in older children and adults

A

flexural surfaces

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3
Q

What is this condition?

A

Contact allergic dermatitis

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4
Q

Common infections associated with eczema? (2)

A

staph. aureus; herpes simplex virus

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5
Q

Difference between contact allergic and irritant dermatitis

A

Irritant does not require prior exposure and may occur due to milder irritants

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6
Q

T cells affected in eczema

A

Th2

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7
Q

Clues that allergic contact dermatitis may be workplace associated?

A

clears up on holiday

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8
Q

More extreme treatment of eczema

A

phototherapy, immunosuppressants and biologic agents

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9
Q

Appearance of eczema herpeticum

A

monomorphic punched out lesions

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10
Q

Condition where eczema and herpes simplex virus are combined

A

eczema herpeticum

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11
Q

Pathogenic mechanism behind allergic contact dermatitis

A

langherhans cells process and present the antigen at the regional lymph nodes and activate naive CD4 T cells. This results in the production of effector and memory T cells which produce a response to future exposures within 48-96 hours.

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12
Q

Atopic eczema is associated with what other diseases? (3)

A

asthma, allergic rhinitis, food allergy

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13
Q

Example of emollients

A

Diprobase, Dermol, Epaderm, E45

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14
Q

Appearance of skin in a person with eczema

A

dry, erythematous, scaling, lichenification, excoriations

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15
Q

Allergic contact dermatitis requires…?

A

prior exposure

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16
Q

Diagnostic criteria for eczema is itching plus 3 or more of…?

A

visible flexural rash (children/adults), history of a flexural rash, PMH or close family history of atopy, generally dry skin, onset before age 2

17
Q

Papule

A

raised area <0.5cm

18
Q

What is this condition called?

A

Atopic eczema

19
Q

Treatment of allergic contact dermatitis?

A

avoidance; topical steroids where more severe; topical calcineurin inhibitors and emollients to moisturise

20
Q

Common condition associated with allergic contact dermatitis?

A

atopic eczema

21
Q

Localisation of a rash associated with allergic contact dermatitis?

A

tends to be localised to areas of exposure

22
Q

Common workforces to be affected by allergic contact dermatitis?

A

hairdresses; beauticians; manual and farm labourers, health care professionals, cleaners, food industry workers

23
Q

Discoid eczema in brief

A

eczema in unusual but well defined disc shape

24
Q

Treatment for eczema herpeticum

A

IV antivirals i.e. aciclovir

25
Q

Protein highly affected in eczema

A

Filaggrin

26
Q

Common presentation of allergic contact dermatitis

A

pruritis, erythema, vesicles/bullae (rare but may also have: urticaria, pustules, lichenoid lesions and ulceration)

27
Q

Cytokines affected by eczema

A

IL - 4, 5, 13

28
Q

Spongiosis

A

oedema between the keratinocytes

29
Q

Appearance of eczema with staph. aureus

A

golden crusting around infected area

30
Q

Distribution of atopic eczema in young babies and infants

A

cheeks, scalp, extensor surfaces, neck

31
Q

Seborhheic eczema in brief

A

appears in oily skin areas, may look like dandruff on scalp, redness and greasy, swollen skin.

32
Q

How might atopic eczema affect quality of life?

A

itching may lead to poor sleep and poor cognitive function, in children this may affect the whole family

33
Q

Common causes of allergic contact dermatitis

A

nickel, plants, topical therapies, chemicals, gold, cobalt

34
Q

Treatment of eczema in the beginning

A

Emolients, avoiding irritants, topical steroids where needed, phototherapy if needed

35
Q

Defining feature of eczema

A

it is itchy

36
Q

Vesicular

A

oedema vesicle <0.5cm

37
Q

What are the scratch marks seen here called?

A

Excoriations