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Dermatology > Psoriasis > Flashcards

Psoriasis Flashcards

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Dermatology Board Prep flashcards
1
Q

What is the genetic component of psoriasis. (2)

A

Polygenic susceptibility.

Arthropathy is associated with HLA B27.

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2
Q

What is arthropathy associated with in psoriasis.

A

HLA B27.

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3
Q

What are some exacerbating factors or psoriasis. (3)

A

Drugs.
Stress.
Infection.

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4
Q

What drugs can exacerbating psoriasis. (4)

A

Antimalarials.
Beta-blockers.
Alcohol.
Lithium.

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5
Q

What can a streptococcal sore throat precipitate.

A

Guttate psoriasis.

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6
Q

What are the subtypes of psoriasis. (4)

A

Stable chronic plaque.
Guttate.
Erythrodermic.
Pustular.

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7
Q

What are the clinical skin signs of chronic plaque psoriasis. (2)

A

Salmon coloured silver scaly lesions often involving the scalp, behind the ear.
Predominantly occur on extensor surfaces, but can occur anywhere.

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8
Q

What are the nail signs of psoriasis. (5)

A 
Nail pitting. 
Onycholysis. 
Nail dystrophy. 
Yellow-brown discoloration. 
Sublingual hyperkeratosis.
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9
Q

What is the Koebner phenomenon.

A

Psoriatic lesions occur over the sites of trauma.

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10
Q

What can the psoriatic lesions look like. (3)

A

Plaques.
Nummular (coin-shaped).
Guttate (raindrop-shaped).

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11
Q

What percentage of patients with psoriasis develop psoriatic arthropathy.

A

1%.

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12
Q

What percentage of the population is affected by psoriasis.

A

2%.

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13
Q

What is psoriasis.

A

A common papulo-squamous disorder.

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14
Q

What is psoriasis characterized by.

A

Well-demarcated, red scaly plaques.

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15
Q

What is the pathogenesis of psoriasis.

A

The skin becomes inflamed and hyperproliferates at about 10 times the normal rate.

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16
Q

What are the two peaks of onset of psoriasis. (2)

A

16-22 is common and is often associated with a positive family history.
Late onset peaks at 55-60.

17
Q

What drugs can make psoriasis worse. (3)

A

Lithium.
Antimalarials.
Rarely beta blockers.

18
Q

What are the main aetiologies of psoriasis. (4)

A

Chronic plaque psoriasis.
Flexural psoriasis.
Guttate psoriasis.
Erythrodermic and pustular psoriasis.

19
Q

What is the most common type of psoriasis.

A

Chronic plaque psoriasis.

20
Q

What percentage of patients with psoriasis will develop arthritis.

A

5-10%.

21
Q

What is the most severe types of psoriasis.

A

erythrodermic and pustular.

22
Q

What is the condition called with erythrodermic and pustular psoriasis occur together.

A

Von Zumbusch psoriasis.

Dermatology (8 decks)

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