psoriasis Flashcards

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1
Q

what is psoriasis

A

chronic multisystem disease that affects promarily the skin and joints

  • waxes and wanes
  • genetic involved
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2
Q

5 types

A
  1. plaque - scaley erythemaous plaques
  2. inverse/flexural - in the skin folds
  3. guttate - presents with drop lesions, 1-10mm salmon-pink papules
  4. erythrodermic - generalized erythema covering nearly entire body
  5. pustular
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3
Q

what often causes pustular

A

steroid withdrawal - can be lifethreatening

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4
Q

what is palmoplantar

A
  • can be either plaque or pustular type

- can be disabling

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5
Q

how is plaque usually presenting

A

symmetric and bilateral

  • auspitz sign - bleeding after scale removal
  • koener - induced by trauma
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6
Q

what is pathogensis

A
  • hyperproliferatie state

- caused by release of cytokines

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7
Q

medical Hx issues

A
  • can be triggered by infection
  • can also have psoriatic arthritis
  • increases risk of CV disease
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8
Q

what meds can induce

A
  • steroid withdrawal
  • BB
  • lithium
  • antimalarials
  • interfereons
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9
Q

key areas

A
  • scalp
  • ears
  • elbows and knees
  • umbilicus
  • gluteal cleft
  • nails
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10
Q

what is most consistent finding in PT with psoriatic arthritis

A

presence of nail pitting

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11
Q

3 nail Sx in all types of psoriais

A
  1. pitting
  2. onycholysis - separation of nail plate from nail bed
  3. subungal hyperkeratosis
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12
Q

Tx for localized

A

high potency steroids

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13
Q

5 factors that affect Tx

A
  1. age
  2. type
    3 site and extent
  3. previous Tx
  4. med conditions
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14
Q

Tx options

A
  1. topicalsteroids
  2. topical calcineurin inhibs
  3. calcipotriene
  4. salicylic acid
  5. coal tar
  • use topicals with occlusion for better penetration
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15
Q

what should not be used

A

oral steroids - will flare up when discontinued

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16
Q

3 systemic Tx

A
  1. phototherapy
  2. oral - methotrexate or cyclosporine
  3. biologics - TNF-a inhibs, IL blockers