Psoriasis Flashcards

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1
Q

Psoriasis

A

Chronic autoimmune condition that causes recurrent symptoms of psoriatic skin lesions

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2
Q

Describe a psoriatic lesion

A

Dry, flaky, scaly, skin lesions

Raised and rough plaques

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3
Q

Where do psoriatic lesions normally occur

A

Over the extensor surfaces of the elbows and knees and on the scalp.

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4
Q

Pathophysiology of psoriasis

A

Rapid generation of new skin cells, resulting in an abnormal build up and thickening of the skin

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5
Q

Types of psoriasis

A

Plaque
Guttate
Pustular
Erthyrodermic

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6
Q

Plaque psoriasis

A

Thickened erythematous plaques with silver scales, commonly seen on the extensor surfaces and scalp

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7
Q

Guttate psoriasis

A

Small raised papules across the trunk and limbs.

Mildly erythematous and slightly scaly

Over time the papules turn into plaques

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8
Q

Who commonly gets guttate psoriasis

A

Children

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9
Q

What triggers guttate psoriasis

A

Streptococcal throat infection

Stress

Medication

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10
Q

How long does guttate psoriasis take to resolve

A

3 - 4 months

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11
Q

Pustular psoriasis

A

Rare severe form

Pustules form under areas of erythematous skin

Can be systemically unwell

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12
Q

Management of pustular psoriasis

A

Medical emergency - admission to hospital

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13
Q

Erythrodermic psoriasis

A

Rare severe form

Extensive erythematous inflamed areas covering most of the surface area of the skin

Skin comes away in large patches (exfoliation) resulting in raw exposed areas

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14
Q

Management of erythrodermic psoriasis

A

Medical emergency - admission to hospital

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15
Q

Signs suggestive of psoriasis

A

Auspitz sign

Koebner phenomenon

Residual pigmentation

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16
Q

Auspitz sign

A

Small points of bleeding when plaques are scraped off

17
Q

Koebner phenomenon

A

Development of psoriatic lesions to areas of skin affected by trauma

18
Q

Residual pigmentation

A

Pigmentation of the skin after the lesions resolve

19
Q

Management of psoriasis

A

Topical steroids

Topical vitamin D analogues (calcipotriol)

Refer to dermatology for:

  • Topical calcineurin inhibitors (tacrolimus)
  • Phototherapy
  • Immunosupressants like methotrexate, azathioprine and ciclosporin
  • Biologics
20
Q

Nail psoriasis signs

A

Nail pitting

Nail thickening

Nail decolourisation

Ridging

Onycholysis

21
Q

Complications of psoriasis

A

Psoriatic arthritis
Nail psoriasis
Mental health implications

22
Q

Comorbidities associated with psoriasis

A
CVD
Obesity
Hyperlipidaemia
HTN
T2DM
23
Q

Investigations for psoriasis

A

Normally clinical diagnosis

Skin biopsy
CVD screen