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MSK > Pseudogout > Flashcards

Pseudogout Flashcards

1
Q

What is pseudogout?

A

Inflammatory arthritis caused by the deposition of calcium pyrophosphate crystals in the synovium

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2
Q

Which joints are commonly affected in pseudogout?

A

Knee
Shoulder
Wrist
Hips

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3
Q

What are the risk factors for pseudogout?

A

Increasing age
Previous joint trauma
Hyperparathyroidism
Haemochromatosis
Acromegaly
Wilson’s disease
Hypomagnesaemia
Hypophophataemia

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4
Q

What is the presentation of pseudogout?

A

Rapid onset of severe joint pain
Joint stiffness
Joint erythema and swelling

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5
Q

What investigations are used in the diagnosis of pseudogout?

A

Joint aspiration - weakly-positively birefringent rhomboid-shaped crystals
Joint XR
Serum bone profile and PTH
Iron studies
Serum magnesium

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6
Q

What changes can be seen on XR in pseudogout?

A

Loss of joint space
Osteophytes
Subarticular sclerosis
Subchondral cysts

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7
Q

What is the management of pseudogout?

A

Anti-inflammatories - NSAIDs (naproxen) or colchicine
Corticosteroid intra-articular injections
Joint replacement

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MSK (18 decks)

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