Protists Flashcards
Which species of Cyclospora is found in humans
What clinical signs are associated
C. cayetanensis
Diarrhea in people in South America
In what animal and organ is Klossiella normally found
In the kidneys of horses and mice, usually nonpathogenic
What are some hosts of Cyclospora
Snakes, primates, rodents, insectivores (and moles)
How is Cyclospora usually transmitted to people?
Ingest contaminated water or produce (raspberries!!!)
Define some terms relative to the life cycle of Protista. Zoite Sporozoite Tropozoite Schizigomy Gametogeny Zygote
Zoite - motile form
Sporozoite - haploid stage
Zygote - diploid stage
Tropozoite - stage once the protist has entered a cell
Schizogony - split asexually (schizizoites are daughter cells of this split)
Gametogeny - sexual reproduction
For Cystoisospora, what stage does the life cycle arrest at
Arrested sporozoite stage
Characterize the oocyst of Cystoisospora
No polar cap
2 sporocysts each with 4 sporozoites in them
What is the prevalence of Cystoisospora in regards to age ranges
More prevalent diseases in young animals
What part of the animal do Sarcosysts live in?
Muscle
What are key features of the Sarcocystis life cycle
Requires a vertebrate intermediate host where schizonts develop in the endothelial cells, then sporulated sporocysts form oocysts that are seen in the muscles
Carnivorous final host where gametogony only occurs in the intestinal cells
Why is EPM only seen in the Americas
The intermediate host is the the opossum… Only 4 species, in Americas
Sheds sporocysts into environment
What is EPM and what organism causes it?
Equine protozoal myeloencephalitis
Sarcocystis neurona
What is one characteristic of EPM infection?
Formation of schizonts in dividing cells in equine (neural) tissues
Cats, skunks, & 9 banded armadillos can have muscle stages
What role do cattle serve in the Besnoitia besnoiti life cycle
Intermediate hosts
What is the final host of most Besnoitia species of veterinary significance
Cats
What are the intermediate hosts of 2 species of Besnoitia besides B. Besnoiti
B. Darlingi - opossums in US
B. Wallacei - rodents in US
Other B. Species affect donkeys, mainly miniature donkeys
What does a facultative heteroxenous life cycle refer to?
Ex. Of one organism that has this type of life cycle.
Can utilize paratenic hosts… Can be completed in a single host or can utilize other hosts for completion of the life cycle
Toxoplasma
In what animal was Toxoplasma gondii first found
A gundi, a small rodent in North Africa
Which life stage of people are most severely affected by Toxoplasma and which life stage of the agent is responsible for disease?
Newborn infants infected in utero
Tachyzoite
What form of Toxoplasma gondii is shed in cat feces
Oocysts
How are people infected with Toxoplasma gondii
Ingest raw/undercooked meat (visceral infection with small cysts in paratenic hosts; with the general exception of beef) or oocysts from contaminated soil or vegetables (enteric infection in cats, shed in feces).
What are the 4 forms that toxoplasma gondii appears as in human hosts
- Chronic infxn with bradyzoites
- Acute disease with multiplying tachyzoites following first exposure
- Infection of infants in utero
- Recrudescence by reactivation of Brady into tachyzoites
What needs to happen for recrudescence of an existing infection to occur?
Immunosupression
When is a fetus in danger of being infected with toxoplasma
When the mother is infected for the very first time while pregnant
Why are signs worse when the fetus is infected during the first trimester
More cells are rapidly dividing
What species of Protista is normally associated with posterior flaccid paralysis in puppies
Neospora caninum
How are most puppies with Neospora caninum derived paralysis infected
Transplacentally
What other species are affected by Neospora caninum, and how
Cow, causes abortions. Usually no repeat abortions.
What are vectors of hepatozoon of different species
Hepatozoon canis and Hepatozoon americanum in dogs transmitted by tick… Rhipicephalus sanguineus and Amblyomma maculatum respectively
Species in rodents vectored by mites
Species in reptiles vectored by mosquitoes
Describe the life cycle of Hepatozoon americanum in reference to its hosts
Ingested by tick as gamonts in blood,
sexual replication in tick gut makes oocysts in body cavity of tick,
Dog eats tick or paratenic host (infected rabbit)
Schizonts occur in various tissues and gamonts in white blood cells