Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Biochem > Proteins > Flashcards

Proteins Flashcards

1
Q

Set of all the proteins expressed by an individual cell at a particular time

A

Proteome

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Except for this amino acid, each amino acid has a carboxyl grp, amino grp and distinct side chain

A

Proline

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

The structure of the _______ dictates the function of amino acid

A

R group

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Hydrogen bonds are through attachment to these elements

A

Sulfur
Nitrogen
Oxygen

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What type of amino acids forms hydrogen bonds?

A

Polar uncharged

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What type of amino acids forms ionic interactions?

A

Charged amino acids

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What type of amino acids forms hydrophobic interactions?

A

Non-Polar

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Charged amino acids

HAGAL

A 
Histidine
Aspartate
Glutamate
Arginine
Lysine
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Polar uncharged amino acids

A

Serine, threonine, tyrosine
Cysteine
Asparagine, Glutamine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Amino acid with smallest side chain

A

Glycine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Amino acid used in the 1st step of heme synthesis

A

Glycine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Carrier of ammonia and carbons of pyrivate from skeletal muscle to liver

A

Alanine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Branched chain amino acids

A

Valine
Leucine
Isoleucine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Branched chain amino acids are Metabolites that accumulate in what disease

A

Maple syrup urine disease

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Precursor of tyrosine

A

Phenylalanine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Accumulates in phenylketonuria

A

Phenylalanine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Largest side chain amino acid

A

Tryptophan

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Amino acid with double ring

A

Tryptophan

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Tryptophan derivatives

A

Trip Mo Siya Noh

Melatonin
Serotonin
Niacin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Precursor of homocysteine

A

Methionine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

Not an amino acid but an imino acid

A

Proline

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

Tyrosine derivatives

A

Pare True Love Does Not Exist To Melanie

Phenylalanine
Tyrosine
L- dopa
Dopamine
Norepi
Epinephrine 
Thyroxine
Melanin
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

Amino acid involved in ammonia formation

A

Glutamine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

Amino acid that participates in the biosynthesis of coenzyme A

A

Cysteine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Q

Cystine contains a lot of

A

Keratin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
26
Q

Precursor of GABA and glutathione

A

Glutamate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
27
Q

Precursor of histamine

Used in diagnosis of folic acid deficiency

A

Histidine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
28
Q

Precursor of crea, urea and NO

A

Arginine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
29
Q

21st amino acid

A

Selenocysteine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
30
Q

All amino acids are chiral except for

A

Glycine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
31
Q

Amino acid that bears no charge at its isoelectric pH

A

Zwitterion

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
32
Q

Amino acid that is considered nutritionally semi essential

A

Arginine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
33
Q

Arginine can be synthesized in what pathway

A

Urea cycle

34
Q

Essential amino acids

A 
PVT TIM HALL always Argues never Tyres
Phenylalanine
Valine
Tryptophan 
Threonine
Isoleucine
Methionine
Histidine
Arginine
Leucine
Lysine
35
Q

This protein structure is determined by a protein’s amino acid sequence

A

Primary structure

36
Q

Partial double bonds that are generally in the trans configuration

A

Peptide bonds

37
Q

Process of identifying the specific amino acid at each position in the peptide chain

A

Sequencing

38
Q

First protein to be sequenced

A

Insulin

39
Q

Folding of short continuous segments of polypeptides into geometrically ordered units

A

Secondary structure

40
Q

Most common secondary structure

Spiral with polypeptide backbone core

A

Alpha helix

41
Q

Amino acid residues that form a zigzag or pleated pattern

A

Beta sheet

42
Q

Supersecondary structures produced by packing side chains from adjacent secondary elements

A

Motifs

43
Q

Also called 3D shape of a protein

A

Tertiary structure

44
Q

Fundamental functional and 3D structural units of polypeptide

A

Domains

45
Q

Specialized group of proteins required for proper folding and prevent aggregation

A

Chaperones

46
Q

Results in unfolding and disorganization of the protein’s secondary and tertiary structure

A

Denaturation

47
Q

Most common and important degenerative disease of the brain

Amyloid plaque
Neurofibrillary tangles

A

Alzheimers

48
Q

This lipoprotein is implicated in the conformational transformation of beta amyloid

A

Apo E

49
Q

Heme protein present in heart and skeletal muscle

A

Myoglobin

50
Q

O2 dissociation curve of hemoglobin and myoglobin

A

Hemoglobin- sigmoidal

Myoglobin- hyperbolic

51
Q

Factors that cause the hemoglobin dissociation curve to shift to the right

A 
CABET
Increased
CO2
Acidity
2,3 BPG
Exercise (O2 demand)
Temperature
52
Q

The release of oxygen from hemoglobin is enhanced when the pH is lowered or when in the presence of increased pCO2

A

Bohr effect

53
Q

Describes when less O2 is bound, the affinity of hemoglobin to CO2 increases

A

Haldane effect

54
Q

Hemoglobin A is seen when the baby is this age

A

8 months old

55
Q

Site of hemoglobin in sequence

A

Yolk sac
Liver
Marrow

56
Q

Form of hemoglobin bound to carbon monoxide in place of oxygen

A

Carboxyhemoglobin

57
Q

Hemoglobin that has increased affinity for cyanide

A

Methemoglobin

58
Q

Also called chocolate cyanosis

A

Methemoglobinemia

59
Q

Treatment for cyanide poisoning

A

Methylene blue

60
Q

Mutation in hereditary spherocytosis

A

Ankyrin

Spectrin

61
Q

Sickle cell disease is from a point mutation in genes

The amino acids interchanged are

A

Valine and glutamate

62
Q

Hemoglobin C disease happens when these are interchanged

A

Lysine and glutamate

63
Q

Which chromosome is affected in alpha thalassemia?

A

Chr 16

64
Q

Which chromosome is affected in beta thalassemia?

A

Chr 11

65
Q

Most abundant protein in the body

A

Collagen

66
Q

Most common type of collagen

A

Type 1

67
Q

Type of collagen in bone and tendon

A

Type 1

68
Q

Type 2 collagen is found in

A

Cartilage

69
Q

Type of collagen found in reticulin:

Skin, blood vessels, uterus

A

Type 3

70
Q

Type 4 collagen is found in the

A

Basement membrane

71
Q

Inherited disorder of collagen characterized by hyperextensibility of skin, increased joint mobility

A

Ehlers Danlos

72
Q

Most common type of Ehlers Danlos

A

Hypermobility type

73
Q

Most serious type of Ehlers Danlos

A

Vascular type

74
Q

Ehlers Danlos has a defect in what type of collagen?

A

Type 3 - most common
Type 1
Type 5

75
Q

Defect in type 1 collagen
Brittle bone disease
Autosomal dominant

A

Osteogenesis imperfecta

76
Q

Genetic disorder where there is a defect in type 4 collagen

A

Alport syndrome

77
Q

Main presenting sign of Alport

Syndrome

A

Hematuria

78
Q

Copper deficiency resulting to kinky hair and growth retardation

A

Menkes disease

79
Q

Autosomal dominant

Mutation in fibrillin gene

A

Marfan

80
Q

Emphysema may be due to this deficiency

A

Alpha 1 anti trypsin

Biochem (7 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions