Enzymes And Bioenergetics Flashcards
Essential for function of enzymes
Co factor
Describes how reaction velocity varies with substrate concentration
Michaelis- Menten equation
Maximal number of substrate molecues converted to product per unit time
Vmax
Substrate concentration at which V1 is half the maximal velocity at a particular concentration of enzyme
Km ( Michaelis constant)
Factors that affect the rate of reaction
Substrate concentration
Temperature
pH
Reciprocal of Michaelis Menten equation
Lineweaver- Burk plot
Type of enzyme inhibitor that binds to enzyme somewhere other than the active site
Noncompetitive
Km and Vmax in a noncompetitive enzyme inhibitor is
Km- unchanged
Vmax- lowered
The transfer and utilization of energy in biologic systems
Bioenergetics
Measure of the change in heat content of reactants and products
Enthalpy
Measure in the change of randomness or disorder of the reactants and products
Entropy
Predicts the direction in which a reaction will spontaneously proceed
Change in free energy
When there is a net _____ of energy, the reaction would be spontaneous
Net loss of energy- exergonic
Energy currency of the cell
ATP
Mas mayaman kay ATP na pwede utangan
PCBC bank
Phosphoenolpyruvate
Carbamoyl phosphate
1,3 Bisphosphoglycerate
Creatine phosphate
Greatest quantitative source of high energy phosphate in aerobic organisms
Oxidative phosphorylation
Final common pathway by which electrons from different fuels of the body flow to oxygen
ETC
Electron transport chain is located in the
Inner mitochondria
Only nonprotein component of ETC
Ubiquinone (CoQ)
The synthesis of ATP in the ETC is through the entry of protons to which complex
Complex V
Barbiturates inhibits which complex in the ETC
Complex I
Cyanide inhibits which complex in the ETC
Complex IV
Carbon monoxide inhibits which complex in the ETC
Complex IV
Dimercaprol inhibits which complex in the ETC
Complex III
