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Biochem > Enzymes And Bioenergetics > Flashcards

Enzymes And Bioenergetics Flashcards

1
Q

Essential for function of enzymes

A

Co factor

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2
Q

Describes how reaction velocity varies with substrate concentration

A

Michaelis- Menten equation

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3
Q

Maximal number of substrate molecues converted to product per unit time

A

Vmax

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4
Q

Substrate concentration at which V1 is half the maximal velocity at a particular concentration of enzyme

A

Km ( Michaelis constant)

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5
Q

Factors that affect the rate of reaction

A

Substrate concentration
Temperature
pH

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6
Q

Reciprocal of Michaelis Menten equation

A

Lineweaver- Burk plot

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7
Q

Type of enzyme inhibitor that binds to enzyme somewhere other than the active site

A

Noncompetitive

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8
Q

Km and Vmax in a noncompetitive enzyme inhibitor is

A

Km- unchanged

Vmax- lowered

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9
Q

The transfer and utilization of energy in biologic systems

A

Bioenergetics

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10
Q

Measure of the change in heat content of reactants and products

A

Enthalpy

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11
Q

Measure in the change of randomness or disorder of the reactants and products

A

Entropy

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12
Q

Predicts the direction in which a reaction will spontaneously proceed

A

Change in free energy

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13
Q

When there is a net _____ of energy, the reaction would be spontaneous

A

Net loss of energy- exergonic

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14
Q

Energy currency of the cell

A

ATP

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15
Q

Mas mayaman kay ATP na pwede utangan

A

PCBC bank

Phosphoenolpyruvate
Carbamoyl phosphate
1,3 Bisphosphoglycerate
Creatine phosphate

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16
Q

Greatest quantitative source of high energy phosphate in aerobic organisms

A

Oxidative phosphorylation

17
Q

Final common pathway by which electrons from different fuels of the body flow to oxygen

A

ETC

18
Q

Electron transport chain is located in the

A

Inner mitochondria

19
Q

Only nonprotein component of ETC

A

Ubiquinone (CoQ)

20
Q

The synthesis of ATP in the ETC is through the entry of protons to which complex

A

Complex V

21
Q

Barbiturates inhibits which complex in the ETC

A

Complex I

22
Q

Cyanide inhibits which complex in the ETC

A

Complex IV

23
Q

Carbon monoxide inhibits which complex in the ETC

A

Complex IV

24
Q

Dimercaprol inhibits which complex in the ETC

A

Complex III

25
Q

Malonate inhibits which complex in the ETC

A

Complex II

26
Q

Final electron acceptor in ETC

A

Oxygen

27
Q

Compounds that increase the permeability of the inner mitochondrial membrane to protons

A

Uncouplers

28
Q

Synthetic uncouplers

A

Aspirin

2,4 dinitrophenol

29
Q

Byproduct of ETC when molecular O2 is partially reduced

A

Reactive oxygen species

30
Q

ATP synthase inhibitors inhibit this complex in the ETC

A

Complex V

31
Q

Inhibits oxidative phosphorylation by inhibiting the transport of ADP in and ATP out of the mitochondria

A

Atractyloside

Biochem (7 decks)

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