Proteins 2

Question 1

Refers to the arrangement / order of amino acids in a polypeptide

Answer 1

Primary structure

Question 2

one-dimensional first step in specifying the 3 dimensional structure of proteins

Answer 2

Primary structure

Question 3

it dictates the secondary, tertiary and quaternary structure of protein

Answer 3

Primary structure

Question 4

Most stable structure

Answer 4

Primary structure

Question 5

• Determines the native and most frequently occurring secondary and tertiary

Answer 5

Primary structure

Question 6

enables the whole chain to fold and curl in such a way to assume its final shape

Answer 6

Sequence (Primary structure)

Question 7

consists of 40 or more amino acid residues

Answer 7

Oligopeptides

Question 8

Conformations of amino acids in localized regions of a polypeptide chain

Answer 8

Secondary structure

Question 9

local folding (exclusive of side chains)

Answer 9

Secondary structure

Question 10

type of Structure with polar interaction

Answer 10

Secondary structure

Question 11

Has INTERMOLECULAR HYDROGEN BONDS

Answer 11

??

Question 12

In the peptide bond that link successive amino acid residues in a polypeptide chains, the electrons are somewhat

Answer 12

Delocalized

Question 13

• The polypeptide backbone has limited conformation flexibility

Answer 13

Secondary structure

Question 14

2 Types of secondary structure

Answer 14

Alpha helix and beta pleated sheet

Question 15

type of secondary structure in which a section of polypeptide chain coils into a spiral

Answer 15

Alpha helix structure

Question 16

2 types of alpha helix (secondary) structure

Answer 16

Left and right handed spiral

Question 17

Stabilizer of Secondary structure

Answer 17

Hydrogen bonds

Question 18

How many amino acids are there per turn of alpha helix

Answer 18

3.6 amino acids

Question 19

distance of every turn / rise

Answer 19

5.4 angstroms along its axis

Question 20

Destabilizer of alpha helix

Answer 20

Proline, hydroxyproline and those that contain aromatic rings

Question 21

In alpha helix and beta pleated sheets, 8 atoms of each peptide bond lie in the same plane. True or False

Answer 21

False, 6 atoms

Question 22

In alpha helix, the N-H amino group and C=O carboxyl group point toward the same direction roughly ____ to the axis of the helix

Answer 22

Parallel

Question 23

In alpha helix R-groups are

Answer 23

pointing OUTWARD from the helix

Question 24

A type of secondary structure in which two polypeptide chains or sections of the same polypeptide chain align parallel to each other

Answer 24

Beta pleated sheets

Question 25

Types of Beta pleated sheets

Answer 25

Parallel and antiparallel

Question 26

contains multiple polypeptide strands consist of line strands of polypeptide whose H-bonding requirements are met by bonding with neighboring strands creating parallel and antiparallel beta sheats

Answer 26

Beta pleated sheets

Question 27

type of beta pleated sheets consists of neighboring chains that is ran in the same direction

Answer 27

Parallel

Question 28

type of beta pleated sheet neighboring chains that ran in opposite direction in which each residues forms 2 HYDROGEN BONDS with neighboring strand

Answer 28

Antiparallel

Question 29

In beta pleated sheets, the r-groups are

Answer 29

in alternating position, first above then below the plane of the sheet

Question 30

Additional structure of secondary structure

Answer 30

Random coil

Question 31

Collagen triple helix consists of

Answer 31

Glycine (1/3), Hydroxylysine and proline (proline can be a destabilizer)

Question 32

Collagen triple helix follows what kind of force of attraction

Answer 32

Vander-wals

Question 33

Collagen is what type of strcture

Answer 33

Secondary - alpha helix structure

Question 34

type of structure that gives The complete three-dimensional arrangement of atoms of a polypeptide chain

Answer 34

Tertiary Structure

Question 35

type of structure that uses nonpolar hydrophobic interaction and vander wals iforce of attraction

Answer 35

tertiary structure

Question 36

type of structure that Gives the overall conformation of an entire polypeptide chain

Answer 36

Tertiary structure

Question 37

Type of structure that gives the Spatial arrangement

Answer 37

tertiary structure

Question 38

Tertiary structure is stabilized by

Answer 38

Hydrogen bond and 4 additional stability

Question 39

type of structure that gives the 3D shape of a protein-- including the regular and irregular structures as well as the spatial arrangement of all its side chains

Answer 39

Tertiary structure

Question 40

type of structure that is fully folded under physiological pH

Answer 40

Tertiary structure

Question 41

Roles of transition metals (d-block series)

Answer 41

For stabilization of protein

Question 42

Metals that form biologically important compounds

Answer 42

Transition metals

Question 43

Coordination compoundsq

Answer 43

???

Question 44

Tertiary structure stabilizer that forms disulfide bonds

Answer 44

Covalent bonds -- Cystine