Proteins Flashcards
Proteins
Side chain have properties 20 different aa Aa exist as different isomers Isomer are 2 or more compounds Alpha C in aa has 4 covalent bonds
Proteins
Highly diverse
Polymers of aa
Aa has an amino group and carboxyl group
Alpha C side chain
Protein
As joined by peptide bonds
Peptide bond is formed in reaction of carboxyl acid
Molecule of h2o is lost called condensation
Protein
Aa have free nh2 or cool group End has free n terminus Free carboxyl group c terminus Protein has own sequence Folded
Protein
No covalent bonds
Ionic bonds
Positive and negative aa
Protein
Hydrophobic being non polar aa Foldup to secondary and tertiary Secondary - 2 proteins fold Polypeptide has backbone Alpha helix - polypeptide twist chain
Protein
Hydrogen bonding of 1aa
Aa exposes on outside
2 or more helical make super helix
Beta sheet- maintained by h bonding
Beta sheets
Aa chains and beta sheet
Found in proteins and anti bodies
Collagen triple helix
Connective tissue
3aa chains
Every 3 aa is glycine
Glycine has smallest chain
Tertiary structure
Proteins fold Hydrophobic Exposed and polar A and b found to amphipathic Side chain and hydrophobic surface
Cont
No solvent
Quaternary structure
Single polypeptide chain Common type of covalent Occur between cysteine residues 2 chains called diner More than 2 chains are called trimers
Cont
Diner has the same chains called homodimer
If chains are different there called hetrodimer
Domains
Folded up
Single chain
Subunits
Encoded by Exon
Function
Mechanical support
Transport
Hormones
Enzymes
