Homeostatis Flashcards
Regulation of plasma glucose
Glucose offers mechanisms Feed back loops Absorption of glucose Plasma glucose can harm the body Plasma glucose levels
Homeostasis
Composition of extra cellular fluid Regulates temp and blood pressure Constant interal Plasma k levels If high limits then existence potential Heart failure Parameter to be regulated Signalling mechanisms
Thermorgulation
Constant internal temp
If above 41c then protein can denature
Below 32c metabolic process
Slow down
Cont
Actions of autonomic nervous system.
Braun called the hypothalamus
Respond to warmth and cold
Increase in activity of sympathic nervous
Cont
Thickness of layer of air trapped in hair
Adipose tissue known as brown fat
ATP converted to heat
Endocrine system
Hormones are gradin ally cells within endocrine glands
Hormonal secretions into bloodstream
Interact with receptor cells
Glucose uptake into live and muscule by insulin
Es
Long lasting effects of gene expression Produce hormones Includes hypothalamus, pituitary, adrenal gland Every cell in body produces signal Cytokines, modulators or transmitters
Type of hormone
Effective in cell signalling
Steroid
Testosterone Oestrogen Small molecules synthesised Cholesterol released Hydrophobic and circulate in the blood bound Carrier proteins DNA and alter gene expression
Polypeptide or protein hormones
2-332. Aa
Often synthesised
Modification and rease
Cell surface receptors
Aa hormones
Aa tyrosine
Stored in cells
Thyroid
Cell signal receptors
First stage of converting the presence of signal molecule
Signal transduction
Cell surface and intercellular
Cell surface receptors
Proteins which scan membrane
Alters activity of intracellular
Leading to an influx of ca2+ ions
Intracellular receptors
Cytoplasm or nucleus DNA binding site Blocked by presence of inhibitory proteins Lipid soluble hormones Transcription to gene expression
Second messenger systems
Signal molecule to a surface receptor Last minutes Interact with intracellular proteins Smooth muscle contraction Ca2+ ions cytoplasm in and out of cell