protein Structure

Question 1

compromise aa residues which fold to adopt a unique structure and function

Answer 1

proteins

Question 2

interior of water soluble proteins are ______ and aa residues with ________ are favored

Answer 2

non-polar and aa residues with hydrocarbon-rich side chain

Question 3

exterior of water soluble proteins are _______ and aa residues with _______ side chains or ________ are predominant here

Answer 3

exterior is polar and aa residues with charged side chains and hydrophilic molecules are predominant

Question 4

fits poorly into helices

Answer 4

proline

Question 5

absorb UV light

Answer 5

tyrosine and tryptophan

Question 6

mutations may disrupt function by altering a ______ ____ or _____ ___

Answer 6

altering a critical contact or altering structure

Question 7

small aa that allows close approach of one part of a protein to another

Answer 7

glycine

Question 8

multiple domains, binds nucleotides with ATP and spans membrane and allow chloride transport

Answer 8

CFTR

Question 9

relatively insoluble in water and are elongated instead of being compact

Answer 9

fibrous protein

Question 10

contains a demosine cross-link

Answer 10

elastin

Question 11

desmosine cross link formed by

Answer 11

lysine residues

Question 12

protein of hair and nails and skin and is very helical

Answer 12

keratin

Question 13

maximum buffering

Answer 13

when the [base]=[acid] at the pKA

Question 14

true or false: closer to pKA, buffering is pooer

Answer 14

false

Question 15

major buffers (3)

Answer 15

bicarbonate
phosphate
proteins

Question 16

molecules that pass through membrane poorly

Answer 16

charged

Question 17

point where pH is net charge is zero

Answer 17

isoelectric point

Question 18

controlled by breathing and affects the blood, pka is a little lower than neutral

Answer 18

bicarbonate

Question 19

found in cells, pka is near neutrality pH 7

Answer 19

phosphate

Question 20

found in blood and in cells; has a wide variety of different side chains at a variety of pKa values

Answer 20

proteins