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renal > prostate cancer > Flashcards

prostate cancer Flashcards

1
Q

2nd most common cancer in males

A

prostate

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2
Q

2nd deadliest cancer in males

A

prostate

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3
Q

most common type of prostate cancer

A

adenocarcinoma

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4
Q

risk factors of prostate cancer

A

age >50
family history
BRCA2

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5
Q

symptoms of prostate cancer

A

mostly asymptomatic
some obstructive sx
back/bone pain if there are METS

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6
Q

initial diagnostic test for prostate cancer

A

DRE

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7
Q

most accurate test for prostate cancer

A

transrectal ultrasound guided needle biopsy

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8
Q

DRE findings for prostate cancer

A

hard nodular asymmetrical prostate

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9
Q

signs of metastatic prostate cancer

A

bone pain
neuro deficits
lymphedema

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10
Q

abnormal PSA threshold

A

> 4 ng/mL

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11
Q

Gleason heading system

A

determines malignant potential of prostate cancer

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12
Q

first number in Gleason tells you

A

the predominant or most plentiful cancer type present on biopsy

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13
Q

second number in Gleason tells you

A

secondary pattern on biopsy

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14
Q

which is worse: Gleason 3+4 or 4+3

A

4+3

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15
Q

what three factors determine prognosis of prostate cancer?

A

pre-tx PSA
Grade group
TNM stage

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16
Q

which pts need a bone scan

A

unfavorable intermediate and high risk pts

17
Q

tx options for localized disease

A 
active surveillance
observation
brachytherapy
external beam radiation
radical prostatectomy
18
Q

treatment for pts with prostate cancer and a life expectancy <10 years

A

observation

19
Q

treatment of advanced prostate cancer

A

external beam radiation therapy
hormonal tx with androgen deprivation (abiraterone)
chemo as a last resort

20
Q

Gleason 9-10 is grade _

A

5

21
Q

very high risk group is which gleason

A

primary Gleason 5

22
Q

GnRH agonist used to treat androgen sensitive prostate cancer

A

leuprolide

23
Q

adverse effects of prostatectomy

A

incontinence

ED

24
Q

treatment of prostate cancer that is resistant after orchiectomy

A

local radiation with EBRT

renal (17 decks)

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