Prolactin Flashcards

1
Q

prolactin

A

protein hormone from anterior pituitary that induces lactation; single chain, 4 alpha-helixes, together w/disulfide bridges

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2
Q

lactation

A

produced by prolactin

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3
Q

alveolus (mammary gland)

A

formed by secretory cells at base of duct network

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4
Q

mammary gland secretory cell

A

grouped into lobules, form alveolus, make milk products

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5
Q

myoepithelial cell

A

squeeze alveolus, push on individual secretory cells, pushes milk to ducts

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6
Q

dopamine neuron (hypophysiotropic factor)

A

releases inhibitory CS

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7
Q

Gi protein

A

intact when DA is not released and gated K+ channel is closed

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8
Q

follicular phase

A

normal production of estrogen

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9
Q

luteal phase

A

normal production of progesterone

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10
Q

estrogen

A

normal production when prolactin is normal

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11
Q

progesterone

A

normal production when prolactin is normal; high when pregnant

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12
Q

amenorrhea

A

prolactin high, estrogen low, progesterone low

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13
Q

bromocriptine

A

synthetic DA; use when high prolactin secretion

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14
Q

haloperidol

A

treatment when prolactin low; DA antagonist

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15
Q

testosterone

A

normal production when prolactin is normal; if low = sperm quality affected

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16
Q

gynecomastia

A

prolactin high, sperm low; mammary glands in males