Biosynthesis 1 Flashcards

1
Q

modified amino acid CS

A

precursor = tyrosine; thyroid hormone = thyroxine; catecholamines

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

polypeptide CS

A

single/double chain of AAs; hydrophilic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

hydrophilic

A

attracted to water

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

hydrophobic

A

resists water

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

catecholamines

A

dopamine, norepinephrine, epinephrine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

essential AA

A

not made by body; tyrosine (precursor for dopamine)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

tyrosine transporter

A

brings tyrosine in

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

tyrosine hydroxylase

A

cytoplasmic protein; converts tyrosine to dopamine; rate limiting enzyme

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

cytoplasmic protein

A

maintain metabolism in living cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

L-amino acid decarboxylase

A

cytoplasmic protein; converts tyrosine to dopamine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

dopamine

A

improves blood flow

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

dopamine transporter

A

DA to enter RSV

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

dopamine B-hydroxylase

A

converts DA to NOR (EPI and NOR)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

norepinephrine

A

treat low blood pressure and heart failure

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

norepinephrine transporter

A

allows NOR to leave RSV (EPI)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

phenylethanolamine n-methyltransferase

A

PNMT; enzyme in cytoplasm (EPI)

17
Q

epinephrine

A

raise glucose in blood

18
Q

epinephrine transporter

A

brings EPI to RSV (EPI)

19
Q

rate limiting step

A

tyrosine hydroxylase

20
Q

negative allosteric interaction

A

tyrosine hydroxylase; DA or NOR enter allosteric binding site = tyrosine to tyrosine

21
Q

active site (of enzyme)

A

where tyrosine attaches; w/out (-) = tyr to L-dopa; w/(-) = tyr to tyr

22
Q

allosteric binding site (of enzyme)

A

outside of active site; DA or NOR in ABS = tyr to tyr

23
Q

DA (-) allosteric factor

A

DA

24
Q

NOR (-) allosteric factor

A

DA

25
Q

EPI (-) allosteric factor

A

DA, NOR, and EPI

26
Q

precursor for catecholamines

A

amino acid tyrosine