Prokinetics Mechanism of action Flashcards

0
Q

Domperidone

A

Peripheral dopamine receptor antagonist

Increses motility and peristalsis

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1
Q

Cisapride

A

Enhances release of acetylcholine at myenteric plexus

Has 5HT4 antagonistic properties, increasing GI motility

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2
Q

Macrolides

A

Stimulate motilin receptors on smooth muscle, activating migrating motor complex

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3
Q

Metoclopramide

A

Antiemetic by blocking dopamine receptors

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