IBS Treatments Side Effects Flashcards

0
Q

Alosetron

A

Constipation in 30% of patients

Ischemic colitis in 0.3%

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1
Q

Tegaserod

A

Long QT

Metabolyte of CYP3A4

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2
Q

Bulk forming laxatives

A

Allergies, flatulence, obstruction

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3
Q

Lubiprostone

A

Diarrhea
Nausea
Vomiting
Fetal loss

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4
Q

Loperamide

A

Abdominal cramps

Toxic megacolon if patient has ulcerative colitis

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5
Q

Linaclotide

A

Severe diarrhea
Pregnancy Class C for maternal death
Kills baby mice

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