Antiemetic Class Mechanisms Flashcards

1
Q

5HT3 antagonist Mechanism of Action

A

5HT3 afferent block in GI tract

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2
Q

Anticholinergic MOA

A

Muscarinic AND dopaminergic receptor antagonist inside cerebellum

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3
Q

NK1 antagonist MOA

A

Substance P receptor antagonist, inside BBB

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4
Q

Antihistamine MOA

A

Sedation, maybe antimuscarinic effects

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5
Q

D2 receptor antagonist MOA

A

CTZ D2 receptor antagonist
Resets GI motility
Sedation

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6
Q

Cannabinoid MOA

A

Sedation, munchies

Antiemetic

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7
Q

Corticosteroid MOA

A

Unknown for antiemetics

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