Antiemetic Class Mechanisms Flashcards
1
Q
5HT3 antagonist Mechanism of Action
A
5HT3 afferent block in GI tract
2
Q
Anticholinergic MOA
A
Muscarinic AND dopaminergic receptor antagonist inside cerebellum
3
Q
NK1 antagonist MOA
A
Substance P receptor antagonist, inside BBB
4
Q
Antihistamine MOA
A
Sedation, maybe antimuscarinic effects
5
Q
D2 receptor antagonist MOA
A
CTZ D2 receptor antagonist
Resets GI motility
Sedation
6
Q
Cannabinoid MOA
A
Sedation, munchies
Antiemetic
7
Q
Corticosteroid MOA
A
Unknown for antiemetics