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Gastrointestinal - Pharmacology > Laxatives and Cathartics Therapeutic Uses and Side Effects > Flashcards

Laxatives and Cathartics Therapeutic Uses and Side Effects Flashcards

0
Q

Bulk laxatives

A

Stool stabilizers: Decrease bowel movements and solidify stools with diarrhea
Decrease pain

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1
Q

Docusate

A

Stool softener in patients who should avoid straining

Constipation with hard, dry stools

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2
Q

Anthraquinones

A

Short term treatment of constipation

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3
Q

Bisacodyl

A

Large intestine treatment of constipation

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4
Q

Castor oil

A

Evacuating bowels

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5
Q

Linaclotide

A

Chronic idiopathic constipation

IBS with constipation

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6
Q

Lubiprostone

A

Chronic constipation

Constipation from IBS

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7
Q

Alvimorpan

A

Constipation caused by opiate therapy

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8
Q

Methylnaltrexone

A

Constipation caused by opiate therapy

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9
Q

Lactulose

A

Constipation, especially when enteric nervous system is disrupted

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10
Q

Side effects of docusate

A

Intestinal obstruction
Diarrhea
Cramping

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11
Q

Side effects of mineral oil

A

Lipid pneumonitis if aspirated

ADEK absorption decrease

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12
Q

Side effects of bulk laxatives

A

Allergies, flatulence, obstruction

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13
Q

Side effects of anthraquinones

A

Abdominal cramps, diarrhea, nausea, vomiting

Melanosis coli

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14
Q

Side effects of Bisacodyl

A

Hypersensitivity
Abdominal pain or obstruction
Nausea vomiting

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15
Q

Side effects of Castor oil

A

Dehydration
Electrolyte imbalance
Uterine contraction

16
Q

Side effects of Linaclotide

A

Severe diarrhea
Maternal death
Increased mortality in juvenile mice

17
Q

Side effects of Lubiprostine

A

Diarrhea
Nausea, vomiting
Fetal loss (Class C)

18
Q

Side effects of Alvimorpan

A

Increased risk for MI

19
Q

Side effects of Methylnaloxone

A

Increased risk for MI

20
Q

Side effects of Lactulose

A

Plasma ammonia decrease

Portal systemic encephalopathy

21
Q

Side effects of Sodium phosphate

A 
Electrolyte imbalances:
Hypokalemia
Hypocalcemia
Hyperphosphatemia
Hypernatremia

Gastrointestinal - Pharmacology (15 decks)

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