Principles of Immunisation Flashcards
What is active immunisation
brought about by a foreign antigen triggering an adaptive immune response within the body
creates immunological memory
initial response is slow but provides quicker defence against recurring infections by the same pathogen
examples of vaccines for active immunity
live organisms (Attenuated) MMR or BCG
killed organism
toxid
recombinant - genetically altered, antigen coding gene is removed and replaced into yeast chromosome
conjugate- antigen as a carbohydrate is bound to a protein ie, strep Pneumoniae, Neisseria Meningitidis, Haemophilus Influenzaem
What is passive immunisation
gives quick and immediate protection but does not create memory
involves inoculating the patient with antibodies specific to the pathogen