Chronic Inflammation

Question 1

list the cell types involved in chronic inflammation

Answer 1

lymphocytes, macrophages, plasma cells, fibroblasts

Question 2

list the major causes of chronic inflammation

Answer 2

arising from acute inflammation - large volume of damage, inability to remove debris, fails to resolve

Arising as a primary lesion - no acute phase, can be result of: autoimmunal disorder, material resistant to cellular digestion, exogenous substances eg. sutures, glass, endogenous substances eg. keratin, hair, necrotic tissue

Question 3

effects of chronic inflammation

Answer 3

scarring and fibrosis

granuloma formation

Question 4

Factors involved in promoting healing and repair

Answer 4

cleanliness

apposition of edges

sound nutrition

metabolic stability and normality

normal inflammatory and coagulation mechanisms