Drug Delivery

Question 1

preparation forms suitable for oral medication

Answer 1

solutions/ suspensions

suspensions

tablets and capsules

enteric coated tablets

Question 2

strengths and weaknesses of solutions

Answer 2

absorbed rapidly

may be given via naso-gastric or PEG tubes

absorption depends on gastric emptying

Question 3

strengths and weaknesses of suspensions

Answer 3

dose can be contained in small volume

good for insoluble/unpalatable drugs

Question 4

strengths and weaknesses of tablets and capsules

Answer 4

absorption depends on the rate at which the tablet breaks down

convenience

accuracy of dose

reproducibility

stability

ease of mass production

Question 5

strengths and weakness of enteric coated tablets

Answer 5

enteric coating delays disintegration until it reaches the small intestine

tablets are coated to: protect tablet from stomach acid, protect the stomach from the drug