Principles of Homeostasis Flashcards

1
Q

what is homeostasis?

A

the relative constancy of the body and the maintenance of constant conditions in the body’s environment
it is how an organism regulates it’s internal environment to maintain stability

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2
Q

what is compensation?

A

the return to homeostasis after being challenged (something deviating from the norm)

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3
Q

what is decompensation?

A

the failure to compensate, adapt, heal (can’t bring it back to stability)

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4
Q

efferent?

A

travelling outwards

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5
Q

what nervous system does homeostasis involve?

A

autonomic nervous system

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6
Q

what does the autonomic nervous system innervate?

A

it innervates smooth muscle, cardiac muscle and glands

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7
Q

what are two nerve fibres connected by?

A

a synapse

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8
Q

positive feedback example - during labour:

A

oxytocin during parturition triggering contractions - oxytocin triggers more muscle contractions which triggers more oxytocin to be release etc.

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9
Q

positive feedback example - during protein digestion:

A

AAs sensed, CCK produced, proteins broken down to produce more AAs so more CCK then produced

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10
Q

examples of negative feedback:

A

temp control
water balance
pH of the blood (acid-base balance)

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11
Q

what does the Juxta-glomerular apparatus stimulate?

A

the RAAS pathway

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12
Q

what does the RAAS pathway result in?

A

sodium retention

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13
Q

parathyroid gland?

A

releases parathyroid gland hormone

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14
Q

what does the release of the parathyroid gland hormone result in?

A

increases calcium ion uptake in intestines and in kidneys and stimulates Ca2+ release from bones

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15
Q

two ways a cell can die?

A

necrosis and apoptosis

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16
Q

apoptosis?

A

controlled cell death, in control of what is happening, cellular suicide, DNA/proteins damaged

17
Q

steps of apoptosis?

A

normal cell –> condensation –> fragmentation –> apoptic bodies

17
Q

stages of necrosis?

A

normal cell, swelling, irreversible swelling and then disintegration

18
Q

morphology of necrosis?

A

random

19
Q

morphology of apoptosis?

A

typical

20
Q

what cells are found in the crypts of the gut?

A

stem cells

21
Q

what are the stem cells found in the crypts of the gut producing?

A

intestinal epithelium - crypt base columnar cells

22
Q

coeliac disease destroys?

A

crypt base columnar cells, the folds flatten out and it is harder for the body to absorb nutrients

23
Q

misfolded protein results in?

A

it forms an enzyme which causes more proteins to misfold just like it

24
Q
A