Inherited diseases

Question 1

spontaneous myoclonic jerks associated with what disease?

Answer 1

lafora disease

Question 2

is lafora disease recessive or dominant?

Answer 2

recessive

Question 3

degenerative myelophathy

Answer 3

complete paralysis of the hind legs

Question 4

inheritance of degenerative myelophathy?

Answer 4

incompletely penetrant autosomal recessive
same as motor neurone diseases in humans

Question 5

effective founder size of toller population?

Answer 5

9.8 / 10 dogs

Question 6

effective founder size?

Answer 6

the number of individuals that an entire population was derived from

Question 7

uric acid?

Answer 7

birds produce it from uretha

Question 8

polygenic traits example?

Answer 8

coat colour for labs

Question 9

polygenic traits?

Answer 9

genes interact or add up to produce one result

Question 10

multifactorial traits?

Answer 10

genetic factors
environmental factors
threshold effect

Question 11

intervertebral disc?

Answer 11

acts as cushions

Question 12

wobbler syndrome?

Answer 12

malformed vertebrae and malformed discs

Question 13

wobbler syndrom AKA?

Answer 13

caudal cervical spondylomyelopathy

Question 14

craniosynostosis

Answer 14

skull case fuses too quickly so brain has to use up rest of skull case

Question 15

irish wolfound before two years old?

Answer 15

bread before seizures

Question 16

what dog breed can be susceptible to parvo virus?

Answer 16

rottweilers

Question 17

irish wolfhound susceptible to?

Answer 17

osteosarcoma

Question 18

dog breed susceptible to brain tumours?

Answer 18

boxers

Question 19

how do you tackle inherited disease in a breed?

Answer 19

don’t breed affected dogs
find the genes - good phenotyping - good controls and accurate diagnostic tests
Breeder, vets and researchers must work together

Question 20

MRS MEDIOCRE BITCH