Epigenetics

Question 1

epigenetics?

Answer 1

the study of changes in gene function that are mitotically and/or meiotically heritable and that do not entail a change in DNA sequence

Question 2

fed pre/post natal high calorie diet? foal born with:

Answer 2

with elevated blood pressure, adiposity, insulin resistance

Question 3

mother who are obese maintain high concentrations of glucose and non essential fatty acids - what does this lead to?

Answer 3

induces epigenetic changes
possible permanent changes
leads to greater adiposity and risk of obesity in later lile

Question 4

what does sub-optimum nutrition in utero lead to?

Answer 4

increased risk of obesity in early childhood

Question 5

insulin resistance?

Answer 5

foals born so they can survive starvation - e.g. our native horses have it as they are genetically adapted to survive nutrient poor environments

Question 6

thrifty gene?

Answer 6

enhanced the chances of survival when food supplies were scarce and intermittent

Question 7

what minerals are lost upon soaking hay?

Answer 7

sodium, potassium and phosphorus

Question 8

no B vitamins as by product?

Answer 8

mess up DNA methylation

Question 9

what can overfeeding calories do to the animal?

Answer 9

changes the way the animal can process food