Principles of Bulk Repackaging and Nonsterile Compounding Part 2

Question 1

What’s the BUD for amoxicillin that was repackaged on October 9, 2016? The manufacturer’s expiration date is June 1, 2017.

Answer 1

Answer: Because of the manufacturer’s expiration date, the BUD for the amoxicillin would be June 1, 2017

Question 2

There are three parts to a nonsterile compound:

Answer 2

Active ingredient
Inactive ingredient(s)
Vehicle, or diluent

Question 3

Nonaqueous formulations have BUDs of less than ____ months or the earliest of the ingredients’ expiration dates.

Answer 3

6

Question 4

Formulations containing water have BUDs of no more than ____ days with refrigeration

Answer 4

14

Question 5

All other formulations have BUDs that are the earlier of ____ days or until the end of therapy

Answer 5

30

Question 6

The compounding surface area should be ____ and nonporous

Answer 6

smooth

Question 7

Excipients are inert ingredients, ____ drug components that are used with the drug to promote effectiveness, absorption, consistency, or other factors

Answer 7

inactive

Question 8

The use of Class A balances involves a number of steps to achieve accurate weighing of substances:

Answer 8

1. Turn the arrest knob to arrest the balance, which means to lock the pans in place to prevent damage by jarring.
2. Level the balance using the adjustable legs.
3. Add weighing papers or boats to the balance and zero out the balance, so the weighing paper and boats aren’t included in the substance weight.
4. Place weights on the right side of the balance then set the balance to reflect the correct weight.
5. Place the substance to be weighed on the left side of the balance, view pointer, and add or remove material until the pointer is in the center.

Question 9

When measuring using a Class A balance, ____ should be used to adjust the weights. Never adjust with your hands.

Answer 9

tweezers

Question 10

When measuring a liquid in a container such as a graduated cylinder, the liquid must be at eye level. The level is read at the meniscus, the ____ of the liquid line in the container

Answer 10

bottom

Question 11

The 20 percent rule is used when choosing the proper measuring container for liquids. This means that no less than ____ mL should be measured in a 100 mL container

Answer 11

20