primary sclerosing cholangitis Flashcards
1
Q
what is primary sclerosing cholangitis
A
inflammation and fibrosis of intra and extra hepatic bile ducts
2
Q
conditions associated with PSC
A
UC!!
also crohns but less common
HIV
3
Q
features of PSC
A
cholestasis- jaundice, raised bilirubin and ALP
RUQ pain
fatigue
4
Q
investigations for PSC
A
ERCP or MRCP- show biliary strictures giving beaded appearance
pANCA positive
5
Q
complications of PSC
A
cholangiocarcinoma
increased risk of colorectal cancer
