Pressure and flow in arteries and veins Flashcards

1
Q

How do you measure arterial pressure?

A

Auscultation of korotkoff sounds using sphygmomanometer

& stethoscope

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What is the series of the sounds you should hear as you increase the pressure in the cuff ?

A

Silence, tapping, thumping, muffled and silence

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What is the advantage of sphygmomanometer
& stethoscope
beign used to measure arterial pressure?

A

Non-invasive and cheap

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What is the disadvantage of sphygmomanometer
& stethoscope
being used to measure arterial pressure?

A

accuracy,
discontinuous
needs care

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What do elastic arteries do in the terms of pressure variation?

A

Elastic arteries act as pressure reservoir

- damps down pressure variations

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What is the pressure wave affected by?

A
  • stroke volume
  • velocity of ejection
  • elasticity of arteries
  • total peripheral resistance
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What is the average normal arterial pressure?

A

120/80mmHg

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

When does the pressure decrease on the pressure wave graph?

A

When blood goes through arterioles as they are resistance vessels

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What is pulse pressure?

A

Distance between systolic and diastolic pressure

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Is there a big or small drop in pressure through arteries?

A

Small drop through arteries (from ~ 95 to 90 mmHg)

low resistance conduit

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Is there a big or small drop in pressure through arterioles?

A

Large drop through arterioles (from ~ 90 to 40 mmHg)

the resistance vessels

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What pushes the blood back through the veins in capillaries?

A

Leaves a small pressure difference pushing blood back through the veins (from ~ 20 to 5 mmHg)
the systemic filling pressure

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What fraction is the pulmonary circulation pressure of the systemic

A

1/5th

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

How is velocity related to total cross section

A

Lower the total cross section, the higher the velocity

fastest in aorta and vena cava, slowest in capillaries

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What are examples of external influences and factors that affect vaso pressure and return?

A
Gravity 
Skeletal msucle pump
Respiratory pump
Venomotor tone
Systemic filling pressure
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

How does gravity affect arteries and veins?

A

Does not affect driving pressure from arteries to veins
Does causes venous distension in legs

Decreases EDV, preload, SV, CO and then MAP

causes orthostatic hypotention

Results in venous collapse in neck and can be used to estimate central venous pressure

17
Q

What can the venous collapse in the neck estimate?

A

Central venous pressure

18
Q

What is the effect of skeletal muscle pump on the pressure and flow in veins?

A

rhythmic vs static exercise
hot guardsmen
deep vein thrombosis
varicose veins

19
Q

What is the effect of venomotor tone on pressure and veins?

A

= state of contraction of the smooth muscle
surrounding the venules and veins
- mobilises capacitance

20
Q

What is the systemic filling pressure?

A

pressure created by ventricles and

transmitted through vascular tree to the veins

21
Q

What does clotting involve?

A

Formation of platelet plug

Formation of fibrin clot by fibronogen into fibrin by thrombin

22
Q

What are the anticlotting mechanisms of the endothelium?

A

Stops blood contacting collagen
-no platelet aggregation

Produces prostacyclin and NO
-both inhibit platelet aggregation

Produces tissue factor pathway inhibitor (TFPI)
-stops thrombin production

Expresses thrombomodulin
-binds thrombin & inactivates it

Expresses heparin
-also inactivates thrombin

Secretes tissue plasminogen activator (t-PA)
-plasminogen = plasmin & digests clot