Prescribing in Liver Disease Flashcards
1
Q
NSAID adverse effect on BP?
A
Raises BP
2
Q
Adverse effect of diuretic?
A
Gout
3
Q
Adverse effect of metoclopramide?
A
Parkinsonism (treat with L-DOPA)
4
Q
What drugs can cause respiratory depression?
A
Sedatives and Opiates
5
Q
Paracetemol in liver disease, glutathione stores?
A
Reduced
6
Q
P4502E1 in alcoholics?
A
Increased
7
Q
Paracetemol dose which is ok in liver disease?
A
1g twice daily (do not exceed 3g)
8
Q
Codeine dose which is okay in liver disease?
A
30mg three times a day
9
Q
Lumiracoxib?
A
COX 2 inhibitor, big cause of drug induced liver injury
10
Q
Sedative which you can give in liver disease?
A
Lorazepam
Oxazepam
Lormetazepam
11
Q
Aminoglycosides?
A
Aminoglycosides are nephrotoxic
12
Q
Problem with quinolones?
A
Epileptogenic