Prescribing in Liver Disease Flashcards

1
Q

NSAID adverse effect on BP?

A

Raises BP

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2
Q

Adverse effect of diuretic?

A

Gout

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3
Q

Adverse effect of metoclopramide?

A

Parkinsonism (treat with L-DOPA)

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4
Q

What drugs can cause respiratory depression?

A

Sedatives and Opiates

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5
Q

Paracetemol in liver disease, glutathione stores?

A

Reduced

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6
Q

P4502E1 in alcoholics?

A

Increased

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7
Q

Paracetemol dose which is ok in liver disease?

A

1g twice daily (do not exceed 3g)

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8
Q

Codeine dose which is okay in liver disease?

A

30mg three times a day

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9
Q

Lumiracoxib?

A

COX 2 inhibitor, big cause of drug induced liver injury

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10
Q

Sedative which you can give in liver disease?

A

Lorazepam
Oxazepam
Lormetazepam

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11
Q

Aminoglycosides?

A

Aminoglycosides are nephrotoxic

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12
Q

Problem with quinolones?

A

Epileptogenic

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