Bronchial Carcinoma Flashcards
Headaches if you get a cerebral metastasis?
Often worse in the morning
Not photophibic
Invasion of T1 by a pancoast tumour can lead to what?
Muscle wasting in the hand
because the tumour has grown into the brachial plexus
What may happen if a lung cancer metastasises to the cortex?
Fit
How could you relieve the odema in the short term caused by a brain metastasis?
High dose steroids e.g. Dexamethasone
Liver function tests particularly abnormal in liver metasases?
Alkaline phosphatase
Features of hypercalcemia?
Headaches, thirst, confusion and constipation
What is the main symptom of hyponatremia?
Confusion
Hyponatremia may occur if a substance similar to ADH is produced
Which cancers can present with thrombophlebitis?
Lung, gastric and pancreatic
Cancer patients have blood with an increased coagulability
Apart from bronchoscopy and a CT guided biopsy, how could you make a tissue diagnosis for lung cancer?
Lymph node aspirate
Aspiration of pleural fluid
What activates pepsinogen to pepsin?
HCl
When does secretion of somatostatin occur?
In between meals
What does pirenzepine do in acid secretion?
these drugs bind competitively
Muscarinic antagonist for the receptor on the paracrine and parietal cell
Decreases acid production
What does ranitidine do?
these drugs bind competitively
Blocks the H2 receptor on the parietal cell
(H2 H2 H2!!)
Decreases acid production
What is omperazole?
Proton pump inhibitor
NSAIDs (including aspirin) blocks COX which results in a decreased formation of what prostaglandin?
(NSAIDs bind irreversibly)
Prostaglangin E
This means that more acid will be produced
