PRES: A New Myeloarchitectonic Map of the Human Neocortex Flashcards

1
Q

What is myeloarchitectonics?

A

A neuroanatomical field focusing on the arrangement and density of myelinated fibers in the cerebral cortex.

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2
Q

How do myeloarchitectonics differ from cytoarchitectonics?

A

Myeloarchitectonics studies myelinated fibers, while cytoarchitectonics examines neuronal cell bodies.

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3
Q

Who developed the only combined cyto- and myeloarchitectonic map of the human cortex?

A

Campbell, in 1905.

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4
Q

What template was used for the new myeloarchitectonic map?

A

The colin27 brain aligned to the MNI305 template.

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5
Q

How many myeloarchitectonic areas does the new map contain?

A

180 areas.

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6
Q

Name one key application of this myeloarchitectonic map.

A

Morphological interpretation of functional neuroimaging results.

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7
Q

Which brain lobe has the most myeloarchitectonic areas?

A

The frontal lobe, with 64 areas.

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8
Q

What technique was used historically to identify fiber layers in the cortex?

A

The Weigert technique.

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9
Q

Who were Oscar and Cécile Vogt?

A

Neuroscientists who significantly contributed to myeloarchitectonic studies between 1910 and 1970.

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10
Q

How does Brodmann’s map compare to the Vogt-Vogt map in complexity?

A

Brodmann’s map is simpler, with about 40 areas, whereas the Vogts proposed around 200 areas.

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11
Q

Why is the colin27 template significant in neuroimaging?

A

It provides a high-resolution standard for cortical mapping and alignment.

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12
Q

What are the ‘outer and inner stripes of Baillarger’?

A

Tangentially organized myelinated fiber layers visible in the cortex.

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13
Q

How were data from multiple brains aligned to the template?

A

Using computer-aided topological transformations.

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14
Q

Which cortex subdivision does the insula belong to in this mapping?

A

It contains 6 myeloarchitectonic areas.

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15
Q

What was the Vogts’ ultimate research goal?

A

To create a unified cytoarchitectonic and myeloarchitectonic map of the cortex.

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16
Q

How did the study address the uneven data availability across lobes?

A

By reconstructing lobar aspect maps when insufficient data were available.

17
Q

What is the role of cytoarchitectonics in complementing myeloarchitectonics?

A

It focuses on cellular structures, which aids in holistic brain mapping.

18
Q

How does this map aid diffusion tractography studies?

A

It provides accurate seed points for mapping fiber tracts.

19
Q

What are ‘regions, areas, and subareas’ in this context?

A

Different levels of cortical parcellation based on myeloarchitectonic features.

20
Q

What is the envisioned ‘supermap’?

A

A comprehensive integration of myeloarchitectonic, cytoarchitectonic, and receptor architectonic maps.