Premidterm Vitamins/cofactors And Shit Flashcards

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0
Q

Copper

A

Needed for:
Lysyl oxidase (ECM)-(hydroxy)lysine to al(hydroxy)lysine of collagen for covalent cross linking.
Complex 4/cytochrome oxidase

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1
Q

Vitamin C

A

Cofactor for prolyl hydroxylase and lysyl hydroxylase (modify prepro-alpha chains of collagen). Deficiency causes scurvy.

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4
Q

B12

A

Needs intrinsic factor from parietal cell for proper absorption, otherwise pernicious anemia

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5
Q

B3

A

Niacin

Used to make NAD+

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6
Q

B2

A

Riboflavin

Used to make FAD

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7
Q

Thiamine

A

TPP
Aka B1
Used in PDH, aKgDH, branched chain fatty acid dehydrogenase, transketolase
Deficiency: Werner-korsakoff syndrome
(Alcoholics) down ATP, increased cardiac output(wet beri-beri) ataxia, cerebral hemorrhage

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8
Q

Lipoic Acid

A

PDH, aKgDH, branched chain fatty acid dehydrogenase

Effected by arsenic poisoning (E2)

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9
Q

PLP

A

Required by glycogen phosphorylase

B6

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10
Q

B7

A

Biotin

Used in pyruvate carboxylase

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