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Medical Biochemistry > Lipids > Flashcards

Lipids Flashcards

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USMLE® Step 1 flashcards
0
Q

Stearate

A

18:0

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1
Q

Palmitate

A

16:0 used in production of lung surfactants

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2
Q

Oleic Acid

A

18:1 omega 9

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3
Q

Linoleic acid

A

18:2 omega 6 dietary essential

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4
Q

Alpha linolenic acid

A

18:3 omega 3 dietary essential

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5
Q

Arachidonic acid

A

20:4 omega 6 part of phosphatidyl inositol

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6
Q

Eicosapentaenoic acid

A

20:5 omega 3 intermediate in humans

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7
Q

Docosahexaenoic acid

A

22:6 omega 3 high fluid micro environment

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8
Q

Phosphatidylcholine

A

Membrane lipid, monolayer in lipoproteins, lung surfactant (dipalmitoyl-PC) synthesis of sphingomyelin formed in liver from dietary choline or methylation of phosphatidylethanolamine (3x SAM)

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9
Q

Phosphatidylethanolamine

A

Found in inner membrane used to make PC with 3x SAM

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10
Q

Phosphatidyl serine

A

Inner leaflet of plasma membrane

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11
Q

Phosphatidylinositol

A

Inner leaflet of plasma membrane contains arachadonic acid 2x phosphorylated to PIP2 cleaved by phospholipase C to DAG and IP3

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12
Q

Cardiolipin

A

Found in inner mitochondrial membrane antigenic (trepanoma pallidum) syphillis

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13
Q

Phospholipid

A

Contains phosphate and glycerol backbone (except sphingomyelin)

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14
Q

Sphingilipid

A

Sphingosine backbone synthesis needs vitamin b6 palmitoyl CoA and serine forms ceremide regulates water permeability of the skin

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15
Q

Sphingomyelin

A

Found in membranes with PC major component of myelin in gray matter and nerves

16
Q

Glycosphingolipids

A

Outer membrane antigens contain 1 sugar are cerebrosides 2 are globosides found in neural tissue

17
Q

Acidic glycosphingolipids

A

Sulfatides cerebrosides with sulfated galactosyl residues (kidney and nerves)
Gangliosides globosudes with addition of NANA n-Acetyl-neuraminic acid found in Cns

Medical Biochemistry (24 decks)

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