(Prelims) MedOrg Exam Pt.3 Flashcards
Involves the loss of sensation preventing person from feeling the pain
Anesthetic
First use of synthetic organic chemicals for modulation of life processes occurred when ____, _____, and _____ were introduced in anesthesia
Nitrous Oxide, Ether, Chloroform
This was used during tooth extraction
Include who used it
Nitrous Oxide
Horace Wells
This was used for exciting a growth on a patient’s neck
Include who used it
Ether
Crawford Long
Used as an anesthetic at St. Bartholomew’s Hospital in London
Chloroform
Used to subside the pain, relief of pain without loss of consciousness
Analgesic
AC of Opium Poppy
Morphine
Potent and euphoric properties of this was used as an analgesic
Opium Poppy
he popularized the use of opium in Europe
Paracelsus
Paracelsus administered opium via?
Laudanum, an alcoholic solution
Side effects of Morphine
HECk of a DREAM
H - Histamine release - Urticaria/Pruritis, Bronchoconstriction
E - Emesis
C - Cardiovascular - Hypotension
D - Depression of cough reflex/antitussive, Decrease in GI motility, sedation
R - Respiratory depression (Most Severe)
E - Euphoria Analgesia
M - Miosis
Made by modification of morphine
Opiates
Give 3 Examples of Opiates
- Heroin (Diacetylmorphine)
- Oxycodone
- Methadone - Milder side effects than morphine
Agents used to induce sleep
Hypnotics
Alcoholic beverages such as what were used to induce sleep
Laudanum and Bromides
He postulated that a carbon atom with 2 ethyl groups would have hypnotic properties, and this was proven by?
Joseph Von Merring
Phenobarbital
Effective as a hypnotic, but also exhibited properties as anticonvulsant
Phenobarbital (Luminol)
Phenobarbital IUPAC name
5-ethyl-5-phenylbarbituric acid
First synthesized in 1908 and discovered as an anticonvulsant in 1938
Phenytoin
Phenytoin is a __________ which is a modification fo barbituric acid molecule
hydantoin
Phenytoin is also known as?
Diphenylhydantoin or
BN: Dilantin
Applied to local areas to numb it, controlling pain without putting patient to sleep
Local anesthetics
True or False:
Local anesthetics can be used for tooth extraction
True
He experimented with several hypnotics and analgesics for use as a local anesthetic in the eye, and also discovered that COCAINE NUMBED THE TONGUE
Carl Koller