(Midterms) Pcol Quiz 1 Pt.1 Flashcards
chronic disorder of brain function
characterized by the recurrent and
unpredictable occurrence of seizure
EPILEPSY
Finite episodes of brain dysfunction resulting
from abnormal discharge of cerebral neurons
Seizure
Idiopathic causes of epilepsy:
tumors
developmental lesions
genetics
EPILEPTIC SEIZURE CLASSIFICATIONS that Begin in a local cortical site (1
hemisphere)
FOCAL ONSET SEIZURES
EPILEPTIC SEIZURE CLASSIFICATIONS that Involves both hemispheres
GENERALIZED ONSET SEIZURES
Preservation of consciousness
(patient can describe in full
detail the attack)
SIMPLE PARTIAL
SEIZURES/ FOCAL
AWARE SEIZURES
Compulsive jerking, psychic
symptoms (altered sensory
perception, illusions,
hallucinations, affect changes)
and autonomic disfunction
(20-60 sec)
SIMPLE PARTIAL
SEIZURES/ FOCAL
AWARE SEIZURES
Purposeless movements such
as lip smacking or hand
wringing (30 sec – 2 mins)
COMPLEX
PARTIAL
SEIZURES/
FOCAL IMPAIRED
AWARENESS
SEIZURES
Loss of awareness and
sustained contractions
of muscles throughout the
body, followed by periods of
muscle contraction altering
with periods of relaxation that last for less than 3
minutes followed by a postictal
period (confusion, tiredness of
variable duration)
GRAND MAL/
GENERALIZED TONIC-CLONIC
SEIZURE
Take note:
Tonic = contractions
Clonic = relaxations
Brief loss of consciousness
(4-20 sec) with no warning
and immediate resumption of
consciousness (no postictal
period
PETIT MAL/
GENERALIZED
ABSENCE
SEIZURE
What are the classifications of antiseizure drugs?
- Sodium Channel Blockers
- Calcium Channel Blockers
- Potassium Channel Opener
- SV2A Receptor Blocker
- Gabaergic Drugs
- GABA-Transaminase inhibitor
- GAT-1 Inhibitor
- Monosaccharide Derivatives
What are the 4 Sodium (Na) Channel Blockers?
- Hydantoin
- Tricylic
- Branched Chain Fatty Acid
- Phenyltriazine