(Midterms) MedOrg Quiz 1 Pt.1 Flashcards
give the Generic name of Strepsils
Dichlorobenzyl Alcohol AmylMetacresol
Strepsils is a combination of 2 anti-infectives, what are these?
Alcohol & Phenol
Introduced antiseptic principles for
use in surgery and posttraumatic
injury
JOSEPH LISTER
Father of Antiseptic Surgery
JOSEPH LISTER
Caused a dramatic decrease in the
incidence of postsurgical infections
He used PHENOL as a wash for the hands, as a
spray on an incision site and on
bandages applied to wounds.
JOSEPH LISTER
Phenol AKA?
Carbolic Acid
Student of Robert Koch
PAUL ERLICH
Father of Chemotherapy
PAUL ERLICH
Discovered that the dyes and arsenicals could stain
target cells SELECTIVELY and that the antimicrobial
properties of the dyes paralleled the staining activity.
PAUL ERLICH
The discovery was the first demonstration of
SELECTIVE TOXICITY
Paul Ehrlich discovered what compound?
SALVARSAN / Compound 606 / Magic Bullet / Arsphenamine
the effective antisyphilytic agent, a
breakthrough in the treatment of serious,
previously untreatable disease.
The property of certain substance to kill one type of
organism while not harming another
SELECTIVE TOXICITY
Killing or inhibiting the growth of microorganisms while
not harming the human beings. (not toxic to humans)
True or False:
Germicides cause resistance
False, they DO NOT cause resistance because they are not systemically asbsorbed
Anti-infective agents that are used locally
GERMICIDES
Compounds that kill (-cidal) or prevent the
growth of (-static) microorganisms when
applied to living tissue.
ANTISEPTICS
● Agent that prevents transmission of infection by
the destruction of pathogenic microorganisms
when applied to inanimate objects.
● Applied on surfaces
DISINFECTANTS
ALCOHOLS AND RELATED COMPOUNDS Mode of Action
Denature CHONs (Proteins) and CHOs (Carbohydrates)
True or False: ALCOHOLS AND RELATED COMPOUNDS should not be applied to wounds
True
Because skin is protein and it would interfere with natural healing and alter structure, so instead IODINE should be used/recommended
What is other name of Alcohol, USP?
Ethanol
AKA: Spiritus vini rectificatus, wine spirit, ethyl
alcohol, grain alcohol
Ethanol or Isopropyl Alcohol
antiseptic, came from a natural source, safer
Ethanol
Ethanol or Isopropyl Alcohol
disadvantage is semi-synthetically produced, disinfectant on inanimate objects
Isopropyl Alcohol
A way to produce ethanol
Fermentation
Uses of Ethanol
Uses:
- Antiseptic
- Preservative
- Rubefacient
- Mild Counterirritant
- Solvent
- Mild Local Anesthesia
Fill in the blanks
95% Ethanol - ____________
nlt 99% Ethanol - ____________
49-50% Ethanol - ____________
70% Ethanol - ____________
95% Ethanol - Absolute
nlt 99% Ethanol - Dehydrated
49-50% Ethanol - Diluted
70% Ethanol - Rubbing Alcohol
Type of ethanol that is available in laboratories and is not effective for killing bacteria
Diluted Alcohol (49-50%)